2023
Ethics Along the Continuum of Research Involving Persons with Disorders of Consciousness
Lewis A, Young M, Rohaut B, Jox R, Claassen J, Creutzfeldt C, Illes J, Kirschen M, Trevick S, Fins J. Ethics Along the Continuum of Research Involving Persons with Disorders of Consciousness. Neurocritical Care 2023, 39: 565-577. PMID: 36977963, PMCID: PMC11023737, DOI: 10.1007/s12028-023-01708-2.Peer-Reviewed Original ResearchConceptsTranslation of researchDisclosure of resultsDisorders of consciousnessContinuum of researchEthical considerationsNeuropalliative careEthics Working GroupInterpretation of outcomesLegally authorized representativeCommunication of resultsComparison of risksStudy designCarePromote recoveryInvolved personsInclusion of minoritiesExclusion criteriaNeurocritical careWorking GroupPersonsInformal reviewOutcomesAwarenessParticipation rightsData protection
2020
The state of clinical outcome assessments for cannabis use disorder clinical trials: A review and research agenda
Loflin MJE, Kiluk BD, Huestis MA, Aklin WM, Budney AJ, Carroll KM, D'Souza DC, Dworkin RH, Gray KM, Hasin DS, Lee DC, Le Foll B, Levin FR, Lile JA, Mason BJ, McRae-Clark AL, Montoya I, Peters EN, Ramey T, Turk DC, Vandrey R, Weiss RD, Strain EC. The state of clinical outcome assessments for cannabis use disorder clinical trials: A review and research agenda. Drug And Alcohol Dependence 2020, 212: 107993. PMID: 32360455, PMCID: PMC7293929, DOI: 10.1016/j.drugalcdep.2020.107993.Peer-Reviewed Original ResearchConceptsClinical outcome assessmentCannabis use disorderClinical trialsOutcome assessmentForms of cannabisCannabis-related harmsCannabis reductionPrimary outcomeFunctional outcomeInterpretation of outcomesClinical endpointsNew pharmacotherapiesPsychomotor impairmentOutcome measuresSelf-report assessmentsDiagnostic criteriaUse disordersOptimal durationCannabis useStudy designBiologic assaysTrialsOptimal outcomesLack of consensusCannabis
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