A cluster of type I interferon-regulated genes associates with disease activity and prognosis in patients with IgA nephropathy
Qu S, Gan T, Wang Y, Qi Y, Zhang Y, Berthier C, Liu L, Shi S, Lv J, Zhang H, Zhou X. A cluster of type I interferon-regulated genes associates with disease activity and prognosis in patients with IgA nephropathy. International Immunopharmacology 2024, 131: 111920. PMID: 38522142, DOI: 10.1016/j.intimp.2024.111920.Peer-Reviewed Original ResearchIFN-regulated genesIFN-scoreIgAN patientsIgA nephropathyIFN-ITubular atrophy/interstitial fibrosisHigher IFN levelsCox regression analysisPathogenesis of IgA nephropathyType I interferonCross-sectional studyGross hematuriaMucosal infectionsRenal outcomesDisease activityIFN scoreInduce high levelsIFN levelsHealthy controlsMesangial hypercellularityIgANI interferonPatientsTherapeutic targetMicrobial infections
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