2025
Delandistrogene Moxeparvovec Gene Therapy in Individuals With Duchenne Muscular Dystrophy: Evidence in Focus
Oskoui M, Caller T, Parsons J, Servais L, Butterfield R, Bharadwaj J, Rose S, Tolchin B, Puskala Hamel K, Silsbee H, Dowling J. Delandistrogene Moxeparvovec Gene Therapy in Individuals With Duchenne Muscular Dystrophy: Evidence in Focus. Neurology 2025, 104: e213604. PMID: 40367405, DOI: 10.1212/wnl.0000000000213604.Peer-Reviewed Original ResearchConceptsDuchenne muscular dystrophyFood and Drug AdministrationClinical trialsImmune-related side effectsMuscular dystrophyFood and Drug Administration approvalFunctional motor outcomePhase 3 clinical trialsTreatment groupsNorth Star Ambulatory Assessment scoresUS Food and Drug AdministrationMotor outcomeClinical trial dataRisk of biasClass I studiesGene therapyTreated patientsAmerican Academy of NeurologyLiver toxicityPrimary outcomeLiver injurySide effectsDrug AdministrationSafety outcomesDose exposureAAN Position
Najib U, Cheng E, Halker Singh R, Ayub N, Nelson S, Bushard P, Jordan J, Sico J, Turbes M, Anderson W. AAN Position. Neurology 2025, 104: e213544. PMID: 40193721, DOI: 10.1212/wnl.0000000000213544.Peer-Reviewed Original ResearchConceptsAmerican Academy of NeurologySafety of opioid prescribingElectronic prescribing of controlled substancesLow back painPrescribing of controlled substancesMisused prescription medicationsPrescribing of opioidsPrescription monitoring programsElectronic prescribingCare teamBack painPrescription medicationsPatient's painOpioid prescribingPrescribing practicesUpstream approachTraumatic brain injuryChronic painOpioid misusePosition statementFinding alternative therapiesPrescribingTeam's needsAmerican AcademyPain disordersSeizures, Driver Licensure, and Medical Reporting Update
Tolchin B, Krauss G, Spanaki M, Joshi C, Pack A, Krishnamurthy K, Bonnie R, Law A. Seizures, Driver Licensure, and Medical Reporting Update. Neurology 2025, 104: e213459. PMID: 40073306, DOI: 10.1212/wnl.0000000000213459.Peer-Reviewed Original ResearchConceptsUniform Law CommissionDepartment of Motor VehiclesEpilepsy Foundation of AmericaLaw CommissionLegal liabilityAdvisory BoardDriving standardElevated riskHealth care practitionersDriver licensureMedical Advisory BoardMedical reportsLicensing criteriaResume drivingUnited StatesMedical conditionsPosition statementMotor vehiclesAmerican Academy of NeurologyStatutesStateReduce confusionCare practitionersConsensus positionLegislationAn update on botulinum toxin treatment of painful diabetic neuropathy, post-traumatic painful neuropathy/neuralgia, post-herpetic neuralgia and occipital neuralgia
Jabbari B, Tohidian A. An update on botulinum toxin treatment of painful diabetic neuropathy, post-traumatic painful neuropathy/neuralgia, post-herpetic neuralgia and occipital neuralgia. Toxicon 2025, 255: 108237. PMID: 39798899, DOI: 10.1016/j.toxicon.2025.108237.Peer-Reviewed Original ResearchConceptsPainful diabetic neuropathyPost-traumatic neuralgiaOccipital neuralgiaPostherpetic neuralgiaMode of treatmentBotulinum toxin treatmentDiabetic neuropathyTreatment of painful diabetic neuropathyPost-herpetic neuralgiaCohort of patientsPain disordersEfficacy criteriaNeuralgiaAmerican Academy of NeurologyLevel of efficacyToxin treatmentAmerican AcademyNeuropathyBotulinum therapyEfficacyPatientsTreatment
2021
The neuroethics of disorders of consciousness: a brief history of evolving ideas
Young M, Bodien Y, Giacino J, Fins J, Truog R, Hochberg L, Edlow B. The neuroethics of disorders of consciousness: a brief history of evolving ideas. Brain 2021, 144: 3291-3310. PMID: 34347037, PMCID: PMC8883802, DOI: 10.1093/brain/awab290.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMulti-Society Task ForceAmerican Congress of Rehabilitation MedicineNational Institute on DisabilityNatural history of recoveryHistory of recoveryAmerican Academy of NeurologyRehabilitation researchRehabilitation medicineTreatment of disorders of consciousnessResponsive careClinical careTaxonomy of disorders of consciousnessAmerican CongressVulnerable populationsIndependent livingProlonged disordersMinimally conscious stateTask ForceAmerican AcademyIncreased awarenessDisability rights perspectiveCareCritically ill patientsBiomedical ethics
2020
Disorders of Consciousness and Disability Law
Fins J, Wright M, Bagenstos S. Disorders of Consciousness and Disability Law. Mayo Clinic Proceedings 2020, 95: 1732-1739. PMID: 32753147, DOI: 10.1016/j.mayocp.2020.02.008.Peer-Reviewed Original ResearchConceptsAmerican Congress of Rehabilitation MedicineNational Institute on DisabilityMulti-Society Task Force ReportMinimally conscious stateUndertreatment of painDisorders of consciousnessRehabilitation of patientsSystematic evidence-based reviewDisability lawAmerican Academy of NeurologyChronic careEvidence-based reviewRehabilitation researchInadequate rehabilitationRehabilitation medicineMedical careNational guidelinesTask Force ReportAmerican CongressNew England JournalPractice guidelinesMedical mainstreamIndependent livingCareInternational disability law
2019
Disorders of Consciousness, Past, Present, and Future
Fins J. Disorders of Consciousness, Past, Present, and Future. Cambridge Quarterly Of Healthcare Ethics 2019, 28: 603-615. PMID: 31405394, DOI: 10.1017/s0963180119000719.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessLegal obligationsPersistent vegetative stateConsciousness literatureNational Institute on DisabilityCognitive motor dissociationMinimally conscious stateCounter-narrativesAmerican Academy of NeurologyVegetative stateMotor dissociationCovert consciousnessObligationsConscious stateDisordersIndependent livingStateWhen No One Notices: Disorders of Consciousness and the Chronic Vegetative State
Fins J. When No One Notices: Disorders of Consciousness and the Chronic Vegetative State. The Hastings Center Report 2019, 49: 14-17. PMID: 31429953, DOI: 10.1002/hast.1030.Peer-Reviewed Original ResearchConceptsNational Institute on DisabilityMulti-Society Task Force ReportDisorders of consciousnessAmerican Academy of NeurologyComprehensive evidence-based reviewEvidence-based reviewRehabilitation researchRehabilitation medicineVegetative stateChronic vegetative stateHealthcare facilitiesTask Force ReportPractice guidelinesIndependent livingPersistent vegetative stateAmerican CollegeAmerican AcademyMisdiagnosis of patientsLevel of consciousnessPermanent vegetative stateForce ReportDiagnostic categoriesPatientsAmericanGuidelines
2018
Botox and Other Neurotoxins
Jabbari B. Botox and Other Neurotoxins. 2018, 19-29. DOI: 10.1007/978-3-319-99945-6_3.Peer-Reviewed Original ResearchClinical characteristicsAmerican Academy of NeurologyClinical studiesClinical trialsClinical investigationClass I
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