Higher ultra-processed food intake is associated with adverse liver outcomes: a prospective cohort study of UK Biobank participants
Zhao L, Clay-Gilmour A, Zhang J, Zhang X, Steck S. Higher ultra-processed food intake is associated with adverse liver outcomes: a prospective cohort study of UK Biobank participants. American Journal Of Clinical Nutrition 2023, 119: 49-57. PMID: 37871746, DOI: 10.1016/j.ajcnut.2023.10.014.Peer-Reviewed Original ResearchConceptsUltra-processed food intakeUltra-processed foodsHigher UPF intakesRisk of nonalcoholic fatty liver diseaseAdverse liver outcomesHigh ultra-processed food intakeNonalcoholic fatty liver diseaseSevere liver diseaseAssociated with increased risk of NAFLDHazard ratioConfidence intervalsUK Biobank participantsEstimate hazard ratiosIncreased risk of NAFLDLiver diseaseProspective cohort studyAssociated with increased riskLiver outcomesIn-hospital recordsCox proportional hazards modelsBody mass indexMultinomial logistic regressionNOVA classificationAssociated with obesityDeath RegistryHigher ultra-processed food intake was positively associated with odds of NAFLD in both US adolescents and adults: A national survey
Zhao L, Zhang X, Steele E, Lo C, Zhang F, Zhang X. Higher ultra-processed food intake was positively associated with odds of NAFLD in both US adolescents and adults: A national survey. Hepatology Communications 2023, 7: e0240. PMID: 37655983, PMCID: PMC10476803, DOI: 10.1097/hc9.0000000000000240.Peer-Reviewed Original ResearchConceptsUltra-processed food intakeUltra-processed foodsHigher UPF intakesHigh ultra-processed food intakeEffects of ultra-processed foodsNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyAssociated with higher oddsLevels of C-reactive proteinNutrition Examination SurveySurvey weight adjustmentsHigher levels of C-reactive proteinOdds of NAFLDElevated body fatAssociated with oddsC-reactive proteinBody mass indexAssociated with lower levelsExamination SurveyWaist circumferenceDietary recallsMultivariate ORDietary dataHigher oddsTransient elastography
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