2024
The association of reduced ejection fraction with the outcomes of endovascular abdominal aortic aneurysm repair
Bellamkonda K, Zogg C, Desai N, Strosberg D, Stone D, Guzman R, Ochoa Chaar C. The association of reduced ejection fraction with the outcomes of endovascular abdominal aortic aneurysm repair. Journal Of Vascular Surgery 2024, 81: 866-876. PMID: 39725244, DOI: 10.1016/j.jvs.2024.12.039.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationCardiomyopathiesDatabases, FactualEndovascular ProceduresFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsStroke VolumeTime FactorsTreatment OutcomeUnited StatesVentricular Function, LeftConceptsEndovascular aneurysm repairEjection fractionReduced EFIschemic cardiomyopathyNormal EFNonischemic cardiomyopathyAneurysm repairOutcomes of endovascular abdominal aortic aneurysm repairOutcomes of endovascular aneurysm repairEndovascular abdominal aortic aneurysm repairAssociated with higher 30-day mortalitySymptomatic abdominal aortic aneurysmElective endovascular aneurysm repairAbdominal aortic aneurysm repairHigher 30-day mortalityVascular Quality Initiative databaseAssociated with high mortalityAortic aneurysm repairVascular Surgery guidelinesAbdominal aortic aneurysmLong-term mortalityVascular Quality InitiativeSeverity of cardiomyopathyReduction of EFSurgery guidelinesAssociation between Body Mass Index and Outcomes in Patients with Newly Diagnosed Acute Myeloid Leukemia Treated with Hypomethylating Agents and Venetoclax
Weiss J, Yates S, Badar T, Patel A, Winer E, Litzow M, Cheng W, Lin C, Shallis R. Association between Body Mass Index and Outcomes in Patients with Newly Diagnosed Acute Myeloid Leukemia Treated with Hypomethylating Agents and Venetoclax. Blood 2024, 144: 1489-1489. DOI: 10.1182/blood-2024-206670.Peer-Reviewed Original ResearchAcute myeloid leukemiaBody mass indexOverall response rateBody mass index groupsSecondary AMLObese ptsHypomethylating agentsEuropean LeukemiaNetMulti-centerOverall survivalMyeloid leukemiaRetrospective studyMass indexNewly diagnosed acute myeloid leukemiaVariable volume of distributionSecondary acute myeloid leukemiaAssociated with higher 90-day mortalityTreatment of acute myeloid leukemiaHigher 30-day mortalityMultivariate Cox regression modelInterquartile rangeComposite remission rateExtensive protein bindingKaplan-Meier methodRisk of early mortalityTrans-arterial embolization for treatment of acute lower gastrointestinal bleeding—a multicenter analysis
Hosse C, Moos M, Becker L, Sieren M, Müller L, Stoehr F, Schaarschmidt B, Barbone G, Collettini F, Fehrenbach U, Hinrichs J, Kloeckner R, Geisel D, Tacke F, Gebauer B, Auer T. Trans-arterial embolization for treatment of acute lower gastrointestinal bleeding—a multicenter analysis. European Radiology 2024, 35: 2746-2754. PMID: 39414657, PMCID: PMC12021941, DOI: 10.1007/s00330-024-11102-x.Peer-Reviewed Original ResearchConceptsTrans-arterial embolizationClinical success rateAcute lower gastrointestinal bleedingLower gastrointestinal bleedingContrast-enhanced computed tomographyAdverse eventsGastrointestinal bleedingSuccess rateBowel surgeryTreating lower gastrointestinal bleedingHigher 30-day mortalityEmergency treatmentIncidence of bowel resectionTechnical success rateThirty-day mortalityPre-interventional imagingTreatment-related variablesEndoscopic therapyComplication rateMethodsConsecutive patientsEmpiric embolizationMulticenter analysisEmbolization techniquesThirty-dayBowel resectionClinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization
Pinto Rodriguez P, Alameddine D, Huttler J, Damara F, Slade M, Cardella J, Guzman R, Chaar C. Clinical Implications of Low Body Mass Index on Endovascular Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 106: 350-359. PMID: 38810726, DOI: 10.1016/j.avsg.2024.02.031.Peer-Reviewed Original ResearchPeripheral vascular interventionsPeripheral arterial diseaseLower body mass indexUnderweight patientsLong-term outcomesBody mass indexNonobese patientsMass indexRetrospective analysis of patientsRate of thrombotic complicationsHigher 30-day mortalityRates of amputation-free survivalRate of reinterventionOutcomes of patientsPeripheral arterial disease patientsAnalysis of patientsKaplan-Meier analysisImpact of malnutritionBaseline demographic characteristicsChronic limb-threatening ischemiaEpidemic of obesityOptimization of nutritionLonger hospital lengthAdverse limb eventsAmputation-free survival
2016
TCF7L2 polymorphism is associated with low nitric oxide release, endothelial dysfunction and enhanced inflammatory response after myocardial infarction
Cintra R, Moura F, Carvalho L, Daher M, Santos S, Costa A, Figueiredo V, Andrade J, Neves F, Quinaglia e Silva J, Sposito A, Group O. TCF7L2 polymorphism is associated with low nitric oxide release, endothelial dysfunction and enhanced inflammatory response after myocardial infarction. BBA Clinical 2016, 5: 159-165. PMID: 27213136, PMCID: PMC4865630, DOI: 10.1016/j.bbacli.2016.03.010.Peer-Reviewed Original ResearchC-reactive proteinFlow-mediated dilationST-elevation MIInterleukin-2Myocardial infarctionInsulin secretionCapacity of insulin secretionNitric oxideAssociated with lower insulin secretionHigher 30-day mortalityNon-diabetic STEMI patientsNon-diabetic patientsT allele carriersTranscription factor 7-like 2Influence clinical outcomesEnhanced inflammatory responseTCF7L2 gene polymorphismPlasma interleukin-2Short-term mortalityEndogenous insulin secretionNitric oxide releaseLower insulin secretionExogenous insulin administrationNitric oxide changesRs7903146 polymorphism
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