Impact of premorbid hypertension and renin-angiotensin-aldosterone system inhibitors on the severity of aneurysmal subarachnoid haemorrhage: a multicentre study
Zhong P, Lu Z, Li Z, Li T, Lan Q, Liu J, Chen S, Wang Z, Huang Q. Impact of premorbid hypertension and renin-angiotensin-aldosterone system inhibitors on the severity of aneurysmal subarachnoid haemorrhage: a multicentre study. Stroke And Vascular Neurology 2024, 10: e003052. PMID: 38889918, PMCID: PMC12107460, DOI: 10.1136/svn-2023-003052.Peer-Reviewed Original ResearchRenin-angiotensin-aldosterone systemWorld Federation of Neurological SurgeonsAneurysmal subarachnoid haemorrhageRenin-angiotensin-aldosterone system inhibitorsHunt-Hess scaleClinical grading scaleClinical outcomesUncontrolled hypertensionGrading scaleWorld Federation of Neurological Surgeons scaleRisk of adverse clinical outcomesHypertension statusElevated risk of poor outcomesSubarachnoid haemorrhageRisk of adverse outcomesComparison to patientsAdverse clinical outcomesRisk of poor outcomesNormal blood pressureMultivariate logistic regressionIntracranial aneurysm ruptureRisk of intracranial aneurysm rupturePremorbid hypertensionSystem inhibitorsMulticentre studyContemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist
Robba C, Busl K, Claassen J, Diringer M, Helbok R, Park S, Rabinstein A, Treggiari M, Vergouwen M, Citerio G. Contemporary management of aneurysmal subarachnoid haemorrhage. An update for the intensivist. Intensive Care Medicine 2024, 50: 646-664. PMID: 38598130, PMCID: PMC11078858, DOI: 10.1007/s00134-024-07387-7.Peer-Reviewed Original ResearchConceptsIntensive care unitAneurysmal subarachnoid haemorrhageRuptured aneurysmsLong-term prognostic factorsRisk of rebleedingIntensive care unit managementRobust clinical evidenceDelayed cerebral ischaemiaExpert clinical experienceSecondary brain damageDeterminants of functional outcomePrognostic factorsASAH patientsPrompt diagnosisHaemodynamic monitoringClinical evidenceMorbidity rateSpecialized centersTreatment strategiesClinical trialsContemporary guidelinesPatient populationFunctional outcomesCare unitCerebral ischaemia
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