2015
Ménétrier’s Disease: Its Mimickers and Pathogenesis
Huh WJ, Coffey RJ, Washington MK. Ménétrier’s Disease: Its Mimickers and Pathogenesis. Journal Of Pathology And Translational Medicine 2015, 50: 10-16. PMID: 26689786, PMCID: PMC4734964, DOI: 10.4132/jptm.2015.09.15.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2005
Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy
Santin AD, Zhan F, Bignotti E, Siegel ER, Cané S, Bellone S, Palmieri M, Anfossi S, Thomas M, Burnett A, Kay HH, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J, Pecorelli S. Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy. Virology 2005, 331: 269-291. PMID: 15629771, DOI: 10.1016/j.virol.2004.09.045.Peer-Reviewed Original ResearchConceptsTissue factor pathway inhibitor-2Normal cervical keratinocytesCDKN2A/p16V-myb myeloblastosis viral oncogene homologDifferential expressionMyeloblastosis viral oncogene homologE2F transcription factor 1Cyclin-dependent kinase inhibitor 2AGene expression profilesMesoderm-specific transcriptNovel candidate molecular markersNovel molecular featuresGene expression dataQuantitative real-time PCRSerine proteinase inhibitorTranscription factor 1V-mybDUTP pyrophosphataseProstaglandin E synthaseTopoisomerase II alphaCandidate molecular markersForkhead box M1Growth factor alphaOligonucleotide microarraysExpression profiles
2004
Synchronous Overexpression of Epidermal Growth Factor Receptor and HER2-neu Protein Is a Predictor of Poor Outcome in Patients with Stage I Non-Small Cell Lung Cancer
Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O’Reilly M, Hong WK, Fidler IJ, Putnam JB, Herbst RS. Synchronous Overexpression of Epidermal Growth Factor Receptor and HER2-neu Protein Is a Predictor of Poor Outcome in Patients with Stage I Non-Small Cell Lung Cancer. Clinical Cancer Research 2004, 10: 136-143. PMID: 14734462, DOI: 10.1158/1078-0432.ccr-0373-3.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma, Bronchiolo-AlveolarAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellDisease ProgressionErbB ReceptorsFemaleFollow-Up StudiesHumansImmunoenzyme TechniquesLung NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPhosphorylationPrognosisReceptor, ErbB-2Retrospective StudiesRisk FactorsSurvival RateTransforming Growth Factor alphaConceptsStage I non-small cell lung cancerNon-small cell lung cancerEpidermal growth factor receptorCell lung cancerSquamous cell carcinomaHER2-neuGrowth factor alphaPhosphorylated epidermal growth factor receptorGrowth factor receptorCell carcinomaLung cancerFactor alphaPathological stage I non-small cell lung cancerFactor receptorPotential prognostic factorsShorter overall survivalPatients' clinical outcomesSynchronous overexpressionHER2-neu overexpressionLung cancer progressionMaximal therapyMetastatic diseaseOverall survivalPrognostic factorsClinical outcomes
1996
Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli.
Jones FE, Jerry DJ, Guarino BC, Andrews GC, Stern DF. Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli. Molecular Cancer Research 1996, 7: 1031-8. PMID: 8853899.Peer-Reviewed Original ResearchConceptsDuctal branchingHRG-alphaMammary epitheliumMammary glandGrowth factorMammary epithelial responsesPrepubescent female miceTerminal end bud formationSecretory productsHRG-betaEnd bud formationGrowth factor alphaGrowth factor treatmentMammary gland developmentFemale miceFactor alphaMammary responseEpithelial responseHistological examinationLobuloalveolar developmentSystemic hormonesTGF-alphaExogenous estradiolVivo proliferationFactor treatmentHeregulin-Induced Growth Factor Receptor Signaling and Breast Carcinogenesis.
Riese D, Stern D. Heregulin-Induced Growth Factor Receptor Signaling and Breast Carcinogenesis. 1996 DOI: 10.21236/ada315700.Peer-Reviewed Original ResearchErbB family receptorsCellular signaling proteinsGrowth factor receptor signalingFamily receptorsBa/F3 cell lineCell linesEGF-like growth factorNeu differentiation factorEpidermal growth factor (EGF) familyGrowth factor familySignaling proteinsFactor familyGrowth factor alphaCellular responsesReceptor phosphorylationReceptor signalingErbB familyDistinct activitiesPairwise combinationsDifferentiation factorEGFBetacellulinHeregulinGrowth factorProtein
1995
Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms.
Scher H, Sarkis A, Reuter V, Cohen D, Netto G, Petrylak D, Lianes P, Fuks Z, Mendelsohn J, Cordon-Cardo C. Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms. Clinical Cancer Research 1995, 1: 545-50. PMID: 9816014.Peer-Reviewed Original ResearchConceptsEpidermal growth factor receptorTGF-alpha expressionTGF-alphaGrowth factor alphaGrowth factor receptorFactor alphaPattern of expressionEpithelial cellsProstate cancer cell growthAutocrine/paracrine interactionsStaining patternRole of EGFRAndrogen-independent tumorsFactor receptorUntreated primary tumorsMalignant prostate epithelial cellsAndrogen-independent diseaseImmunohistochemical staining patternHomogeneous staining patternProstate cancer progressionMalignant epithelial cellsPrimary prostate tumorsCancer cell growthAndrogen-independent conditionGrowth factor pathways
1992
The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor
Bosenberg M, Pandiella A, Massagué J. The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor. Cell 1992, 71: 1157-1165. PMID: 1473151, DOI: 10.1016/s0092-8674(05)80064-9.Peer-Reviewed Original Research
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