2023
79. A LARGE-SCALE GENOME-WIDE ASSOCIATION STUDY OF COCAINE USE DISORDER
Deak J, Zhou H, Levey D, Galimberti M, Farajzadeh L, Hougaard D, Jennings M, Davis L, Sanchez-Roige S, Demontis D, Børglum A, Kranzler H, Gaziano M, Stein M, Gelernter J. 79. A LARGE-SCALE GENOME-WIDE ASSOCIATION STUDY OF COCAINE USE DISORDER. European Neuropsychopharmacology 2023, 75: s99. DOI: 10.1016/j.euroneuro.2023.08.184.Peer-Reviewed Original ResearchGenome-wide association studiesLarge genome-wide association studiesGWS lociBackground Genome-wide association studiesAssociation studiesLarge-scale genome-wide association studiesTissue expression analysisGenetic architectureGWAS analysisIndividuals of AfricanGWAS discoverySingle locusExpression analysisGenetic dataChromosome 11Silico analysisGenetic discoveriesMillion Veteran ProgramChromosome 13Biological understandingLociEuropean ancestryBiological componentsVeteran ProgramNovel findings
2013
NCK2 Is Significantly Associated with Opiates Addiction in African‐Origin Men
Liu Z, Guo X, Jiang Y, Zhang H. NCK2 Is Significantly Associated with Opiates Addiction in African‐Origin Men. The Scientific World JOURNAL 2013, 2013: 748979. PMID: 23533358, PMCID: PMC3603435, DOI: 10.1155/2013/748979.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsNCK2 geneGenome-wide significant associationGenome-wide significant levelWide association studyGene-based methodsNumerous genetic variantsGWAS discoveryChromosome 2Association studiesNck2Genetic variantsGenesNucleotide polymorphismsComplex diseasesFirst evidenceGenetic disordersDiscoverySignificant levelsPolymorphismVariantsSubstantial effort
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