2019
Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis
Smith PH, Assefa B, Kainth S, Salas-Ramirez KY, McKee SA, Giovino GA. Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis. Nicotine & Tobacco Research 2019, 22: 307-316. PMID: 31204787, PMCID: PMC7161928, DOI: 10.1093/ntr/ntz067.Peer-Reviewed Original ResearchConceptsAfrican American smokersSmoking cessationMenthol cigarette useAmerican smokersMenthol useUS smokersCigarette useComprehensive tobacco control effortCross-sectional studyNon-menthol usersPublic health benefitsTobacco control effortsEffect sizeBlack/African AmericanMentholated cigarettesMenthol banLower oddsSmokersMeta-analysisSignificant associationCessationLower likelihoodHealth benefitsQuantitative summaryStudy sample
2016
A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke
Jensen KP, Smith AH, Herman AI, Farrer LA, Kranzler HR, Sofuoglu M, Gelernter J. A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. Molecular Psychiatry 2016, 22: 242-249. PMID: 27067016, PMCID: PMC5390815, DOI: 10.1038/mp.2016.43.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack or African AmericanCadherinsDiagnostic and Statistical Manual of Mental DisordersFemaleGene Expression RegulationGenome-Wide Association StudyHumansMaleMultigene FamilyNicotinePolymorphism, Single NucleotideProtocadherinsRecurrenceSmokingSmoking CessationSubstance Withdrawal SyndromeTobacco Use DisorderWhite PeopleConceptsNicotine withdrawalSingle nucleotide polymorphismsNovel smoking cessation treatmentsAfrican AmericansSmoking cessation treatmentNicotine withdrawal symptomsOvernight smoking abstinenceEuropean American smokersFrontal cortex tissueΓ geneCessation treatmentTobacco smokingSmoking abstinenceWithdrawal symptomsAbstinent smokersAmerican smokersΓ gene expressionNicotine infusionSmoking urgesInfusion studiesSmokersMRNA expressionRisk allelesCortex tissueBrief questionnaire
2015
A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans
Jensen KP, DeVito EE, Herman AI, Valentine GW, Gelernter J, Sofuoglu M. A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans. Neuropsychopharmacology 2015, 40: 2813-2821. PMID: 25948103, PMCID: PMC4864657, DOI: 10.1038/npp.2015.131.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood PressureCognition DisordersCotinineFemaleGenome-Wide Association StudyHeart RateHumansMaleMiddle AgedNerve Tissue ProteinsNeuropsychological TestsNicotineNicotinic AgonistsPolymorphism, Single NucleotideReceptors, NicotinicSmokingSubstance Withdrawal SyndromeSurveys and QuestionnairesConceptsAversive effectsHeavy smokingRisk allelesSmoking-related disordersAfrican American smokersCHRNA5-CHRNA3Doses of nicotineHigh nicotine doseNicotine administrationIntravenous doseNicotine effectsNicotine doseAmerican smokersWithdrawal severityOvernight abstinenceAcute responseAA subjectsCardiovascular reactivityCHRNB4 gene clusterNicotineEuropean AmericansAversive responsesAdministration sessionsSmokingCognitive performance
2014
Prospective Evaluation of Factors Predicting Nicotine Withdrawal Symptoms Among Korean Americans
Kim SS, Fang H, McKee SA, Ziedonis D. Prospective Evaluation of Factors Predicting Nicotine Withdrawal Symptoms Among Korean Americans. The Journal Of Smoking Cessation 2014, 11: 154-162. PMID: 26413165, PMCID: PMC4582669, DOI: 10.1017/jsc.2014.20.Peer-Reviewed Original ResearchMinnesota Nicotine Withdrawal ScaleKorean American smokersNicotine withdrawal symptomsWithdrawal symptomsMore withdrawal symptomsAmerican smokersGreater riskNicotine replacement therapySmoking cessation interventionCessation interventionsProspective evaluationReplacement therapyDisturbed sleepIntensive treatmentTwo-armWithdrawal ScaleAbstinence statusSymptomsWeekly assessmentsSmokersFirst weekWomenSmokingHigh rateWeeks
2013
COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers
Herman AI, Jatlow PI, Gelernter J, Listman JB, Sofuoglu M. COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers. The Pharmacogenomics Journal 2013, 13: 490-497. PMID: 23459442, PMCID: PMC3675163, DOI: 10.1038/tpj.2013.1.Peer-Reviewed Original ResearchConceptsVal/Val genotypeAbstinent smokersVal genotypeGreater systolic blood pressureOvernight abstinent smokersVal158Met polymorphismSystolic blood pressureDoses of nicotineCatechol-O-methyltransferase (COMT) Val158Met polymorphismVal/ValEuropean American smokersNegative subjective effectsCOMT Val158Met polymorphismBlood pressureSmoking cessationAA smokersRisk factorsAmerican smokersIntravenous nicotineWithdrawal severityOvernight abstinenceSmokersNicotine addictionNicotine useSubjective effects
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