2015
Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta‐analysis
Singh S, Khera R, Allen AM, Murad MH, Loomba R. Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta‐analysis. Hepatology 2015, 62: 1417-1432. PMID: 26189925, DOI: 10.1002/hep.27999.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsModerate-quality evidenceNonalcoholic steatohepatitisObeticholic acidLobular inflammationBallooning degenerationVitamin ERelative riskComparative effectivenessBiopsy-proven nonalcoholic steatohepatitisLow-quality evidenceUse of pentoxifyllineIndirect treatment comparisonFuture comparative trialsHigh-quality evidenceConfidence intervalsQuality of evidenceDistinct histological featuresRecommendations AssessmentSecondary outcomesPrimary outcomeCombination therapyFibrosis stageHistological featuresComparative trialsPharmacological interventions
2014
Imaging and Functional Testing to Assess Clinical and Subclinical Neurological Events After Transcatheter or Surgical Aortic Valve Replacement A Comprehensive Review
Spaziano M, Francese DP, Leon MB, Généreux P. Imaging and Functional Testing to Assess Clinical and Subclinical Neurological Events After Transcatheter or Surgical Aortic Valve Replacement A Comprehensive Review. Journal Of The American College Of Cardiology 2014, 64: 1950-1963. PMID: 25444149, DOI: 10.1016/j.jacc.2014.07.986.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementAortic valve replacementNeurological eventsValve replacementFuture comparative trialsFuture prospective studiesProspective studyPoor prognosisComparative trialsSubclinical cognitive declineSurrogate endpointsCognitive declineTesting modalitiesTAVRTranscatheterOperator experienceModalitiesFunctional testingImagingPrognosisClinicalSymptomsIncidenceComprehensive reviewEndpoint
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