Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
de Arce K, Ribic A, Chowdhury D, Watters K, Thompson G, Sanganahalli B, Lippard E, Rohlmann A, Strittmatter S, Missler M, Hyder F, Biederer T. Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions. Nature Communications 2023, 14: 459. PMID: 36709330, PMCID: PMC9884278, DOI: 10.1038/s41467-023-36042-w.Peer-Reviewed Original ResearchConceptsPrefrontal cortexDKO miceSynCAM 1Aberrant neuronal activityDendritic spine numberPrefrontal cortex synapsesSynapse organizersSynapse numberMature brainNeuronal activityKnockout miceSpine numberSynapse developmentCognitive functionTrans-synaptic complexesImmunoglobulin family membersMiceFamily membersSynapsesLRRTM1Behavioral domainsHippocampusCognitive tasksConcerted roleCortexNetwork-wide aberrant neuronal activity in patients with mood disorders: associations with cognitive impairment and functional disability
Damgaard V, Mariegaard J, Macoveanu J, Sankar A, Petersen J, Frøkjær V, Kessing L, Jørgensen M, Knudsen G, Miskowiak K. Network-wide aberrant neuronal activity in patients with mood disorders: associations with cognitive impairment and functional disability. Neuroscience Applied 2023, 2: 102914. DOI: 10.1016/j.nsa.2023.102914.Peer-Reviewed Original Research
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