2023
Isoform Function Prediction Based on Heterogeneous Graph Attention Networks
Guo K, Li Y, Chen H, Shen H, Yang Y. Isoform Function Prediction Based on Heterogeneous Graph Attention Networks. 2023, 00: 522-527. DOI: 10.1109/bibm58861.2023.10386048.Peer-Reviewed Original ResearchIsoform function predictionFunction predictionIsoform functionGene OntologyMechanisms of gene regulationFunctions of isoformsProtein language modelsFunctional labelsProtein sequencesGO annotationsGene regulationSequence featuresGO termsMRNA moleculesIsoform levelsGene levelBiological processesGenesIsoformsSpecies datasetInteraction dataIntricate mechanismsProteinHeterogeneous graph attention networkAnnotation
2015
Exploiting ontology graph for predicting sparsely annotated gene function
Wang S, Cho H, Zhai C, Berger B, Peng J. Exploiting ontology graph for predicting sparsely annotated gene function. Bioinformatics 2015, 31: i357-i364. PMID: 26072504, PMCID: PMC4542782, DOI: 10.1093/bioinformatics/btv260.Peer-Reviewed Original ResearchConceptsFunction prediction algorithmsPrediction algorithmVariety of algorithmsFunctional labelsOntology graphCross-validation experimentsOverfitting problemGraph structurePrevious stateGene functionAlgorithmAnnotation catalogsTens of thousandsMolecular interaction networksFunction predictionOntology databasePoor predictive performanceAnnotationLabelsPredictive performanceGene Ontology databaseInformationLarge numberGO termsInteraction networks
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