Increased phosphorylation of the renal Na+-Cl− cotransporter in male kidney transplant recipient patients with hypertension: a prospective cohort
Rojas-Vega L, Jiménez-Vega A, Bazúa-Valenti S, Arroyo-Garza I, Jiménez J, Gómez-Ocádiz R, Carrillo-Pérez D, Moreno E, Morales-Buenrostro L, Alberú J, Gamba G. Increased phosphorylation of the renal Na+-Cl− cotransporter in male kidney transplant recipient patients with hypertension: a prospective cohort. American Journal Of Physiology. Renal Physiology 2015, 309: f836-f842. PMID: 26336164, DOI: 10.1152/ajprenal.00326.2015.Peer-Reviewed Original ResearchConceptsHypertensive patientsUrinary exosomesPosttransplant hypertensionHistory of acute rejectionKidney transplant recipient patientsTacrolimus trough blood levelsPatients treated with tacrolimusAmbulatory 24-h blood pressure monitoringAdult kidney transplant recipientsTacrolimus-induced hypertensionTacrolimus trough levelsTrough blood levelsNa+-Cl- cotransporterTransplant recipient patientsKidney transplant recipientsDevelopment of hypertensionProspective cohort studyBlood pressure monitoringImmunosuppressive therapyNCC expressionHigh blood pressureTrough levelsAcute rejectionKidney allograftsTransplant recipients
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