Structural insights into HIV-2 CA lattice formation and FG-pocket binding revealed by single-particle cryo-EM
Cook M, Freniere C, Wu C, Lozano F, Xiong Y. Structural insights into HIV-2 CA lattice formation and FG-pocket binding revealed by single-particle cryo-EM. Cell Reports 2025, 44: 115245. PMID: 39864060, PMCID: PMC11912512, DOI: 10.1016/j.celrep.2025.115245.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHIV-2Features of human immunodeficiency virusHIV-2 CAHost factor interactionsImmunodeficiency virusHIV-1Human immunodeficiency virus capsidFunctionalized liposomesCapsid proteinHigh-resolution structuresSingle-particle cryo-EMCA assemblyCA hexamersFactor interactionsViral genomeCA lattice
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