2019
Hepatic resection of solitary HCC in the elderly: A unique disease in a growing population
Zarour LR, Billingsley KG, Walker BS, Enestvedt CK, Orloff SL, Maynard E, Mayo SC. Hepatic resection of solitary HCC in the elderly: A unique disease in a growing population. The American Journal Of Surgery 2019, 217: 899-905. PMID: 30819401, DOI: 10.1016/j.amjsurg.2019.01.030.Peer-Reviewed Original ResearchConceptsSolitary hepatocellular carcinomaPrognostic nutritional indexHepatic resectionElderly patientsUnique diseaseLow prognostic nutritional indexMedian Child-Pugh scoreTumor size 5Child-Pugh scoreGrade III complicationsHalf of patientsRecurrence-free survivalSolitary HCCExtrahepatic recurrenceProspective databaseR0 resectionIntrahepatic recurrenceMajor hepatectomyMedian survivalOverall survivalViral hepatitisLow morbidityMedian ageClinicopathologic dataClinicopathologic differences
2007
Predictive Molecular Markers for Colorectal Cancer Patients With Resected Liver Metastasis and Adjuvant Chemotherapy
Lassmann S, Tang L, Capanu M, Brabletz T, Schöpflin A, Hausen A, Gonen M, Kemeny N, Shia J, Klimstra D, Werner M. Predictive Molecular Markers for Colorectal Cancer Patients With Resected Liver Metastasis and Adjuvant Chemotherapy. Gastroenterology 2007, 133: 1831-1839. PMID: 18054556, DOI: 10.1053/j.gastro.2007.08.075.Peer-Reviewed Original ResearchConceptsResection of liver metastasesResectable liver metastasesHepatic arterial infusionLiver metastasesColorectal cancer patientsColorectal cancerHepatic recurrenceOverall survivalCyclin D1Arterial infusionQuantitative RT-PCR dataRT-PCR dataSurvivin messenger RNA levelsClinically relevant patient subgroupsAssociated with overall survivalLow cyclin D1Microdissected tumor cellsPredictive molecular markersRT-PCRRelevant patient subgroupsSurvivin messenger RNAReverse-transcription polymerase chain reactionMessenger RNA levelsExtrahepatic recurrenceSystemic irinotecan
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