2024
Core Concepts in Pharmacoepidemiology: Quantitative Bias Analysis
Brown J, Hunnicutt J, Ali M, Bhaskaran K, Cole A, Langan S, Nitsch D, Rentsch C, Galwey N, Wing K, Douglas I. Core Concepts in Pharmacoepidemiology: Quantitative Bias Analysis. Pharmacoepidemiology And Drug Safety 2024, 33: e70026. PMID: 39375940, DOI: 10.1002/pds.70026.Peer-Reviewed Original ResearchConceptsQuantitative bias analysisBias analysisValidity of study findingsPharmacoepidemiological studiesRobustness of studiesEffects of medicationStudy designEffect estimatesResidual biasStudy findingsSelection biasConfoundingEstimated effectsPotential biasPharmacoepidemiologyBiasMedicationCore conceptsStudyMeasurement errorA mediation analysis framework based on variance component to remove genetic confounding effect
Dong Z, Zhao H, DeWan A. A mediation analysis framework based on variance component to remove genetic confounding effect. Journal Of Human Genetics 2024, 69: 301-309. PMID: 38528049, DOI: 10.1038/s10038-024-01232-x.Peer-Reviewed Original ResearchMediation analysis frameworkSingle nucleotide polymorphismsMediation analysisPleiotropic single nucleotide polymorphismsUK Biobank dataConfounding effectsTrait pairsBiobank dataIndividual-levelEpidemiological studiesCausal effectsGenetic signalsEstimated effectsLinear regressionNucleotide polymorphismsStandard errorData analysisGenetic correlationsPhenotypeIndirect effectsPleiotropyVariance componentsOutcomesRegressionA scalar-on-quantile-function approach for estimating short-term health effects of environmental exposures
Zhang Y, Chang H, Warren J, Ebelt S. A scalar-on-quantile-function approach for estimating short-term health effects of environmental exposures. Biometrics 2024, 80: ujae008. PMID: 38477485, PMCID: PMC10934338, DOI: 10.1093/biomtc/ujae008.Peer-Reviewed Original ResearchConceptsEmergency departmentAir pollutionHealth effects of environmental exposuresShort-term health effectsAnalysis of air pollutionStochastic Human ExposureAmbient air pollutionEnvironmental epidemiology studiesEffects of environmental exposuresAggregate health outcomesPopulation-level exposureHealth outcomesED visitsPopulation exposureHuman exposureExposure heterogeneitySpatial variationEpidemiological studiesEnvironmental exposuresPollutionHealth analysisEstimated effectsEffects of short-termVisitsQuantile function
2016
Gender, Position of Authority, and the Risk of Depression and Posttraumatic Stress Disorder among a National Sample of U.S. Reserve Component Personnel
Cohen G, Sampson L, Fink D, Wang J, Russell D, Gifford R, Fullerton C, Ursano R, Galea S. Gender, Position of Authority, and the Risk of Depression and Posttraumatic Stress Disorder among a National Sample of U.S. Reserve Component Personnel. Women's Health Issues 2016, 26: 268-277. PMID: 26899583, PMCID: PMC5008021, DOI: 10.1016/j.whi.2016.01.001.Peer-Reviewed Original ResearchConceptsReserve component personnelPosttraumatic stress disorderFemale officersMilitary authoritiesDeployment-related posttraumatic stress disorderPositions of authorityU.S. military operationsInteraction of genderRisk of depressionMale officersStress disorderProbability of posttraumatic stress disorderNationally Representative SampleSocial positionRisk of posttraumatic stress disorderLogistic regression modelsNational sampleProportion of womenOccupational rolesGenderMilitary operationsRepresentative sampleSocial supportEstimated effectsTrauma exposure
2010
Part 2. Association of daily mortality with ambient air pollution, and effect modification by extremely high temperature in Wuhan, China.
Qian Z, He Q, Lin H, Kong L, Zhou D, Liang S, Zhu Z, Liao D, Liu W, Bentley C, Dan J, Wang B, Yang N, Xu S, Gong J, Wei H, Sun H, Qin Z. Part 2. Association of daily mortality with ambient air pollution, and effect modification by extremely high temperature in Wuhan, China. Research Report 2010, 91-217. PMID: 21446212.Peer-Reviewed Original ResearchConceptsCause-specific mortalityDaily cause-specific mortalityAssociation of daily mortalityAmbient air pollutionAir pollutionGeneralized additive modelInternational Classification of DiseasesMortality dataDaily mortalityEffect modificationEffect estimatesPM10 effectsStatistically significant associationFixed-site air monitoring stationsNatural causesPM10 daily concentrationsLevels of PM10Studies of air pollutionAir monitoring stationsICD-9Daily mean concentrationsEnvironmental Monitoring CenterAir pollution levelsEstimated effectsExposure-response relation
2007
Exploring uncertainty of the change from ICD-9 to ICD-10 on acute mortality effects of air pollution
Qian Z, He Q, Lin H, Kong L, Liao D, Gong J, Bentley C, Wei H. Exploring uncertainty of the change from ICD-9 to ICD-10 on acute mortality effects of air pollution. Environment International 2007, 34: 248-253. PMID: 17854896, DOI: 10.1016/j.envint.2007.08.006.Peer-Reviewed Original ResearchConceptsEffects of air pollutionICD-9ICD-10Effect estimates of air pollutantsCause-specific mortalityAcute mortality effectsAir pollutionKappa statisticEstimated effectsICD-10 codesEstimates of air pollutionMortality dataRespiratory mortalityICD codesAir pollution mortalityEffect estimatesGeneralized additive modelMortality effectsConcordance ratePollutionMortalityAdditive modelICDKappaStatistically
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