Mesocortical dopamine neurons: High basal firing frequency predicts tyrosine dependence of dopamine synthesis
Tam S, Elsworth J, Bradberry C, Roth R. Mesocortical dopamine neurons: High basal firing frequency predicts tyrosine dependence of dopamine synthesis. Journal Of Neural Transmission 1990, 81: 97-110. PMID: 2363911, DOI: 10.1007/bf01245830.Peer-Reviewed Original ResearchConceptsMesoprefrontal DA neuronsDA neuronsTyrosine administrationDA levelsCingulate cortexPrefrontal cortexTyrosine hydroxylationAnxiogenic β-carbolineDA metabolite levelsDA terminal fieldsEndogenous DA levelsMesocortical DA neuronsMesocortical dopamine neuronsVivo tyrosine hydroxylationMidbrain DA neuronsTyrosine hydroxylase activityTransmitter outflowDA metabolitesDA synthesisDopamine neuronsFG 7142Dopamine synthesisTerminal fieldsTyrosine availabilityHigh doses
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply