2010
Effect of capsaicin on potassium conductance and electromotility of the guinea pig outer hair cell
Wu T, Song L, Shi X, Jiang Z, Santos-Sacchi J, Nuttall A. Effect of capsaicin on potassium conductance and electromotility of the guinea pig outer hair cell. Hearing Research 2010, 272: 117-124. PMID: 21044673, PMCID: PMC3387680, DOI: 10.1016/j.heares.2010.10.010.Peer-Reviewed Original ResearchConceptsOuter hair cellsTRPV-1 channelsHair cellsPrimary sensory neuronsEffects of capsaicinGuinea pig outer hair cellsSensory neuronsPharmacological actionsCapsaicinPotassium conductancePotent blockerPharmacological propertiesDirect actionNovel actionCochlear amplificationK conductanceAuditory effectsClassic activatorAuditory receptionCellsNociceptionElectromotilityBlockersNew findingsNeurons
1992
Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin.
LaMotte R, Lundberg L, Torebjörk H. Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin. The Journal Of Physiology 1992, 448: 749-764. PMID: 1593488, PMCID: PMC1176226, DOI: 10.1113/jphysiol.1992.sp019068.Peer-Reviewed Original ResearchConceptsDuration of painMagnitude of painC-nociceptorsCapsaicin injectionMechanical hyperalgesiaIntradermal injectionTopical applicationReceptive fieldsC-mechanoheat nociceptorsEffects of capsaicinMean discharge rateCutaneous hyperalgesiaHyperalgesic areaUnchanged responsivenessBackground painAlgesic substancesPeroneal nerveNociceptor excitabilityNociceptor responsesPain thresholdMechanical stimuliNociceptor dischargeIntense painConcomitant painAwake humans
1987
Capsaicin‐induced excitation of locus coeruleus neurons
HAJÓS M, JANCSÓ G, ENGBERG G. Capsaicin‐induced excitation of locus coeruleus neurons. Acta Physiologica 1987, 129: 415-420. PMID: 3577824, DOI: 10.1111/j.1748-1716.1987.tb08086.x.Peer-Reviewed Original ResearchConceptsLocus coeruleusPrimary afferentsAdult ratsHigh dosesPontine nucleus locus coeruleusCapsaicin-induced excitationSigns of tachyphylaxisLocus coeruleus neuronsEffects of capsaicinNucleus locus coeruleusLC firing rateMarked excitationCoeruleus neuronsLC neuronsAnalgetic effectControl ratsLow dosesCapsaicinHistological dataElectrophysiological techniquesFiring rateSilver impregnation techniqueRatsSensory processingDoses
1986
Effects of capsaicin on central monoaminergic mechanisms in the rat
Hajós M, Svensson K, Nissbrandt H, Obál F, Carlsson A. Effects of capsaicin on central monoaminergic mechanisms in the rat. Journal Of Neural Transmission 1986, 66: 221-242. PMID: 3023547, DOI: 10.1007/bf01260916.Peer-Reviewed Original ResearchConceptsAcute capsaicin treatmentCapsaicin treatmentSpinal cordSubstantia nigraCentral monoaminergic mechanismsLevels of DADA synthesis rateEffects of capsaicinDose-dependent mannerLevels of dopaCapsaicin injectionDOPAC levelsMonoaminergic mechanismsNaive animalsPreoptic regionSecond injectionChronic effectsCordCapsaicinAdult animalsRatsLevels of NaMonoaminesDisappearance rateBody temperature
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply