2023
Determinants of muscle function and health-related quality of life in patients with endogenous hypercortisolism: a cross-sectional study
Li D, Zhang C, Saini J, Singh S, Nathani R, Thangamuthu K, Suresh M, Atkinson E, Achenbach S, Van Gompel J, Young W, Bancos I. Determinants of muscle function and health-related quality of life in patients with endogenous hypercortisolism: a cross-sectional study. European Journal Of Endocrinology 2023, 189: 40-49. PMID: 37327378, PMCID: PMC10376436, DOI: 10.1093/ejendo/lvad069.Peer-Reviewed Original ResearchConceptsMild autonomous cortisol secretionQuality of lifeReduced muscle strengthCushing's syndromeMuscle strengthEndogenous hypercortisolismComponent scoresPhysical component of SF36Sit-to-stand test performanceHealth-related quality of lifeSF36 mental component scoreMuscle functionSeverity scoreReference subjectsMental component scorePhysical component scoreHealth-related qualityAutonomous cortisol secretionClinical severity scoreMuscle strength impairmentCross-sectional studyDeterminants of muscle functionStrength impairmentsAdrenal CSEctopic CS
2015
Mifepristone Treatment of Cushing’s Syndrome in a Pediatric Patient
Banerjee R, Marina N, Katznelson L, Feldman B. Mifepristone Treatment of Cushing’s Syndrome in a Pediatric Patient. 2015, 136: e1377-e1381. PMID: 26459648, DOI: 10.1542/peds.2015-0684.Peer-Reviewed Original ResearchConceptsCushing's syndromeMifepristone treatmentPediatric patientsMedical treatment of CSPatients died of progressionPreexisting type 1 diabetesTreatment of Cushing's syndromeHormone secreting tumorsOral potassium replacementMetastatic neuroendocrine carcinomaGlucocorticoid receptor antagonismGlucocorticoid receptor antagonistEffects of hypercortisolismTreatment of CSLimited life expectancyPoor functional statusType 1 diabetesEctopic CSDose escalationSignificant adverse effectsNeuroendocrine carcinomaRadiation therapyPatient diedSecreting tumorsReceptor antagonism
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