2021
Preventing Transfusion-Transmitted Babesiosis
Bloch EM, Krause PJ, Tonnetti L. Preventing Transfusion-Transmitted Babesiosis. Pathogens 2021, 10: 1176. PMID: 34578209, PMCID: PMC8468711, DOI: 10.3390/pathogens10091176.Peer-Reviewed Original ResearchTransfusion-transmitted babesiosisBlood donor testingHealthy blood donorsIntra-erythrocytic parasitesDonor surveillanceTransfusion transmissibleDonor testingHigh morbidityTransfusion recipientsSevere babesiosisBlood donorsBlood supplyBlood safetyHigh riskGlobal epidemiologyHuman babesiosisCausative agentMolecular assaysUnited StatesBabesiosisInfectionRiskMajor riskImmunopathogenesisMorbidity
2020
Impact of Screening and Treatment of Ureaplasma species on Hyperammonemia Syndrome in Lung Transplant Recipients: A Single Center Experience
Roberts SC, Bharat A, Kurihara C, Tomic R, Ison MG. Impact of Screening and Treatment of Ureaplasma species on Hyperammonemia Syndrome in Lung Transplant Recipients: A Single Center Experience. Clinical Infectious Diseases 2020, 73: e2531-e2537. PMID: 33068392, PMCID: PMC8563172, DOI: 10.1093/cid/ciaa1570.Peer-Reviewed Original ResearchConceptsLung transplant recipientsLung transplantUreaplasma sppHyperammonemia syndromePolymerase chain reactionTransplant recipientsUreaplasma speciesSingle-center experienceBronchoalveolar lavage cultureRecipients of organsNegative screening testImpact of screeningFuture confirmatory studiesEmpiric therapyNew onsetLung donorsCenter experienceDonor testingUrine cultureLavage cultureMental statusAntimicrobial therapyTransplantPatientsScreening testInfection with Ureaplasma spp in Lung Transplant Recipients is Donor-Derived
Roberts S, Bharat A, Kurihara C, Ison M. Infection with Ureaplasma spp in Lung Transplant Recipients is Donor-Derived. The Journal Of Heart And Lung Transplantation 2020, 39: s47. DOI: 10.1016/j.healun.2020.01.1220.Peer-Reviewed Original ResearchLung transplant recipientsUreaplasma sppHyperammonemia syndromeTransplant recipientsPositive donorsBronchoalveolar lavageMethods Consecutive patientsNorthwestern Memorial HospitalTime of implantationMicrobial confirmationConsecutive patientsDonor testingConclusions InfectionMemorial HospitalRisk factorsAntimicrobial therapyLTxRsResults SixtyMurine modelNegative testingPatientsActive malesPurpose Recent studiesInfectionHuman subjects
2019
1771. Donor-derived Ureaplasma Infection Increases Mortality in Lung Transplant Recipients
Roberts S, Bharat A, Kurihara C, Bhorade S, Ison M. 1771. Donor-derived Ureaplasma Infection Increases Mortality in Lung Transplant Recipients. Open Forum Infectious Diseases 2019, 6: s653-s653. PMCID: PMC6809047, DOI: 10.1093/ofid/ofz360.1634.Peer-Reviewed Original ResearchDonor-derived infectionTime of LTxLung transplant recipientsHyperammonemia syndromeUreaplasma sppTransplant recipientsDonor screeningPCR testingPre-transplant screeningRetrospective cohort studyRenal replacement therapyBronchoalveolar lavage cultureNegative screening testNorthwestern Memorial HospitalSPSS Statistics version 25.0Donor transmissionEmpiric therapyCohort studyRetrospective cohortDonor testingUrine cultureLavage cultureReplacement therapyMemorial HospitalMental statusFatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution
Balbuena‐Merle R, West FB, Tormey CA, Hendrickson JE. Fatal acute hemolytic transfusion reaction due to anti‐B from a platelet apheresis unit stored in platelet additive solution. Transfusion 2019, 59: 1911-1915. PMID: 30865314, DOI: 10.1111/trf.15240.Peer-Reviewed Original ResearchConceptsGroup B patientsHemolytic transfusion reactionsDirect antiglobulin testB patientsTransfusion reactionsApheresis unitsBlood group B patientsRelapsed acute myeloid leukemiaAcute hemolytic transfusion reactionAnti-human globulin phaseHigh lactate dehydrogenaseAnti-human globulinAcute myeloid leukemiaRecipient testingDonor testingRecipient variablesExtravascular hemolysisPlatelet transfusionsTransfusion recipientsAntibody screenHigh bilirubinPLT transfusionsAntiglobulin testBlood productsMyeloid leukemia
2016
Transfusion support for the oncology patient
Schulz W, Snyder E. Transfusion support for the oncology patient. 2016, 574-580. DOI: 10.1002/9781119013020.ch50.ChaptersOncology patientsTransfusion supportTransfusion-transmitted diseasesSafety of transfusionTA-GVHDTransplant patientsAdverse eventsDonor testingAppropriate therapyABO incompatibilityPatient populationTransfusion therapyOncologic disordersMajor therapyPatientsTransfusion servicesCellular antigensBlood componentsTherapyFrequent exposureTransfusionSpecific assessmentRiskAlloimmunizationImmunomodulation
2012
A Consolidated Biovigilance System for Blood, Tissue and Organs: One Size Does Not Fit All
Pruett TL, Blumberg EA, Cohen DJ, Crippin JS, Freeman RB, Hanto DW, Mulligan DC, Green MD. A Consolidated Biovigilance System for Blood, Tissue and Organs: One Size Does Not Fit All. American Journal Of Transplantation 2012, 12: 1099-1101. PMID: 22487495, DOI: 10.1111/j.1600-6143.2011.03907.x.Peer-Reviewed Original ResearchConceptsOrgan transplant recipientsLimited organ availabilityPublic health servicesTransplant recipientsDonor testingOrgan availabilityWaiting listClinical practiceHealth servicesFormal recommendationsTransfer of organsDisease transmissionBloodOrgansOverall benefitTissueTransplantationSupport effortsRecipients
2010
Nucleic Acid Testing (NAT) of Organ Donors: Is the ‘Best’ Test the Right Test? A Consensus Conference Report
Humar A, Morris M, Blumberg E, Freeman R, Preiksaitis J, Kiberd B, Schweitzer E, Ganz S, Caliendo A, Orlowski J, Wilson B, Kotton C, Michaels M, Kleinman S, Geier S, Murphy B, Green M, Levi M, Knoll G, Segev D, Brubaker S, Hasz R, Lebovitz D, Mulligan D, O’Connor K, Pruett T, Mozes M, Lee I, Delmonico F, Fischer S. Nucleic Acid Testing (NAT) of Organ Donors: Is the ‘Best’ Test the Right Test? A Consensus Conference Report. American Journal Of Transplantation 2010, 10: 889-899. PMID: 20121734, DOI: 10.1111/j.1600-6143.2009.02992.x.Peer-Reviewed Original ResearchConceptsNucleic acid testingOrgan donorsRisk factorsAcid testingInsufficient evidenceRoutine nucleic acid testingConsensus Conference reportDonor-derived infectionRisk of deathBehavioral risk factorsPotential organ donorsRisk of transmissionCandidate listingsHCV screeningDonor testingOrgan utilizationFalse-positive resultsOrgan offerProspective screeningDonor organsScreening modalityDonor lossWaiting listRapid turnaround timeTissue donors
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