2015
DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine
Shin MS, You S, Kang Y, Lee N, Yoo SA, Park K, Kang KS, Kim SH, Mohanty S, Shaw AC, Montgomery RR, Hwang D, Kang I. DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine. The Journal Of Immunology 2015, 195: 2861-2869. PMID: 26276874, PMCID: PMC4561204, DOI: 10.4049/jimmunol.1500877.Peer-Reviewed Original ResearchConceptsDNA methylationDifferential expressionGene expressionCellular traitsEpigenetic mechanismsGene promoterGenome-wide DNA methylationDistinct traitsDNA methylation statusIndividual gene expressionMigratory capacityAutocrine amplification loopImportant biological outcomesPotential biological implicationsMammalian cellsMethylationMethylation statusAmplification loopBiological outcomesTraitsBiological implicationsPromoterEffector memoryExpressionT cells
2009
Evolution of the neocortex: a perspective from developmental biology
Rakic P. Evolution of the neocortex: a perspective from developmental biology. Nature Reviews Neuroscience 2009, 10: 724-735. PMID: 19763105, PMCID: PMC2913577, DOI: 10.1038/nrn2719.Peer-Reviewed Original ResearchConceptsEvo-devo approachSpecies-specific adaptationsExtinct common ancestorsNew cell typesSpecies-specific differencesMutations of genesProliferative ventricular zoneMammalian evolutionDistinct migratory pathwaysCommon ancestorDevelopmental biologyCell divisionNew traitsNew cell subtypesNeural stem cellsProtomap hypothesisMouse embryosNew cytoarchitectonic areasTranscriptional factorsUnique cognitive abilitiesGene expressionDifferential enlargementDistinct traitsMigratory pathwaysCortical evolution
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply