Choroidal congestion mouse model: Could it serve as a pachychoroid model?
Matsumoto H, Mukai R, Hoshino J, Oda M, Matsuzaki T, Ishizaki Y, Shibasaki K, Akiyama H. Choroidal congestion mouse model: Could it serve as a pachychoroid model? PLOS ONE 2021, 16: e0246115. PMID: 33507997, PMCID: PMC7843010, DOI: 10.1371/journal.pone.0246115.Peer-Reviewed Original ResearchConceptsPachychoroid spectrum diseasesRetinal pigment epitheliumVortex vein congestionVortex veinsSpectrum diseaseChoroidal vesselsUltra-widefield indocyanine green angiographyDilated outer choroidal vesselsDilation of choroidal vesselsMouse modelRPE flatmountsVein congestionDilated vortex veinsOuter choroidal vesselsIndocyanine green angiographyInflammatory response-related genesWild type miceOptical coherence tomographyTissue sectionsDay 7 groupChoroidal congestionChoroidal thickeningPachychoroid featuresRPE degenerationMacular disorders
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