2022
Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants
Jang J, Lee S, Ko K, Abe S, Rahman S, Saito E, Islam R, Sawada N, Shu X, Koh W, Sadakane A, Tsuji I, Kim J, Oze I, Nagata C, Tsugane S, Cai H, Yuan J, Gao Y, Ozasa K, Matsuyama S, Kanemura S, Shin A, Ito H, Wada K, Sugawara Y, Chen Y, Ahsan H, Boffetta P, Chia K, Matsuo K, Qiao Y, Rothman N, Zheng W, Inoue M, Kang D, Park S. Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants. Cancer Epidemiology Biomarkers & Prevention 2022, 31: 1727-1734. PMID: 35793701, PMCID: PMC9489277, DOI: 10.1158/1055-9965.epi-22-0051.Peer-Reviewed Original ResearchConceptsBody mass indexNon-cardia gastric cancerGastric cancer riskIntestinal-type gastric cancerAssociation of underweightGastric cancerCancer riskHazard ratioMass indexCox proportional hazards regression modelProportional hazards regression modelsHazards regression modelsConfidence intervalsEarly-onset gastric cancerDiffuse-type gastric cancerCardia gastric cancerGastric cancer casesObesity groupUnderweight groupBMI groupsHistologic subtypeCohort participantsCancer casesAnatomic locationShaped associations
2016
Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population
Lin X, Hu D, Chen G, Shi Y, Zhang H, Wang X, Guo X, Lu L, Black D, Zheng XW, Luo X. Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population. Cancer Genetics 2016, 209: 215-222. PMID: 27160021, DOI: 10.1016/j.cancergen.2016.04.003.Peer-Reviewed Original ResearchConceptsGastric cancerSoutheast Chinese populationThrombospondin-2Thrombospondin-4MRNA expressionChinese populationHuman GC tumorsMouse stomach tissuesDiffuse-type gastric cancerCase-control setsClinicopathological featuresTumor sizePoor prognosisReal-time PCRGC tumorsUnfavorable genotypesPrognosis predictionGC casesMouse stomachModest associationStomach tissueCancer developmentGC riskMRNA overexpressionHuman stomach
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