2015
Outbreak Investigation of Leptospirosis in Padaviya, Sri Lanka
Ramsey A, Rubin-Smith J, Norwich A, Katumuluwa S, Hettiarachchi A, Wimalage S, Danushka W, Madushanka T, Nadeeshani A, Thilakarathna C, Sewwandi L, Malhari T, Sirisena P, Agampodi S. Outbreak Investigation of Leptospirosis in Padaviya, Sri Lanka. Anuradhapura Medical Journal 2015, 9: 23-26. DOI: 10.4038/amj.v9i2.7532.Peer-Reviewed Original ResearchNumber of casesCases of leptospirosisDiagnosis of leptospirosisRegional Health AuthorityRenal compromiseCardiovascular symptomsClinical presentationRetrospective reviewResultsA totalSame hospitalHigh prevalenceBase hospitalHospital staffPatientsHealth authoritiesOutbreak investigationLeptospirosisTropical diseasesPrevious outbreaksHypotensionBradycardiaRecent outbreakAdmissionHospitalParticular outbreak
2014
Validity of a commercially available IgM ELISA test for diagnosing acute leptospirosis in high endemic districts of Sri Lanka
Agampodi S, Thevanesam V, Senaratne T. Validity of a commercially available IgM ELISA test for diagnosing acute leptospirosis in high endemic districts of Sri Lanka. Sri Lankan Journal Of Infectious Diseases 2014, 4: 83. DOI: 10.4038/sljid.v4i2.6952.Peer-Reviewed Original ResearchIgM ELISADiagnosis of leptospirosisConvalescent samplesImmunoglobulin M enzymeDays of illnessComparison groupCases of leptospirosisIgM ELISA kitResultsThe study sampleDepartment of MicrobiologyCare diagnostic testsFebrile patientsAcute leptospirosisFever patientsAcute samplesFaculty of MedicineHuman leptospirosisDay 14Disease confirmationELISA kitLeptospirosisPatientsDiagnostic testsImmunosorbent assayStudy sample
2009
Evaluation of surveillance case definition in the diagnosis of leptospirosis, using the Microscopic Agglutination Test: a validation study
Dassanayake D, Wimalaratna H, Agampodi SB, Liyanapathirana VC, Piyarathna T, Goonapienuwala BL. Evaluation of surveillance case definition in the diagnosis of leptospirosis, using the Microscopic Agglutination Test: a validation study. BMC Infectious Diseases 2009, 9: 48. PMID: 19386085, PMCID: PMC2679753, DOI: 10.1186/1471-2334-9-48.Peer-Reviewed Original ResearchConceptsSurveillance case definitionMicroscopic agglutination testCase definitionNegative predictive valuePredictive valueClinical featuresMAT titresAgglutination testDays of feverAcute febrile illnessMethodsThe study populationTeaching Hospital KandyPositive predictive valueDiagnosis of leptospirosisPositive MAT resultsFebrile illnessMedical wardsResultsA totalHospital KandyStudy populationBlood samplesConclusionThis studyPatientsDiagnostic accuracyLeptospirosis
2005
Clinical Spectrum of Pulmonary Involvement in Leptospirosis in a Region of Endemicity, with Quantification of Leptospiral Burden
Segura ER, Ganoza CA, Campos K, Ricaldi JN, Torres S, Silva H, Céspedes MJ, Matthias MA, Swancutt MA, Liñán R, Gotuzzo E, Guerra H, Gilman RH, Vinetz JM, Consortium P. Clinical Spectrum of Pulmonary Involvement in Leptospirosis in a Region of Endemicity, with Quantification of Leptospiral Burden. Clinical Infectious Diseases 2005, 40: 343-351. PMID: 15668855, PMCID: PMC2366057, DOI: 10.1086/427110.Peer-Reviewed Original ResearchConceptsPulmonary involvementFebrile patientsAcute respiratory distress syndromeMost fatal casesSevere pulmonary manifestationsRespiratory distress syndromePopulation-based studyEvidence of exposureDiagnosis of leptospirosisRegions of endemicityPulmonary complicationsMultiorgan failurePulmonary manifestationsPresumptive treatmentDistress syndromePulmonary hemorrhageSerologic testingIgM antibodiesClinical spectrumPulmonary casesFatal casesQuantitative real-time PCRReal-time PCRAntileptospiral antibodiesLeptospiral burden
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