2025
Association of delayed asthma diagnosis with asthma exacerbations in children
Wi C, Ryu E, King K, Kwon J, Bublitz J, Park M, Chiarella S, Greenwood J, Pongdee T, Myers L, Nordlund B, Sohn S, Sagheb E, Kshatriya B, Watson D, Liu H, Sheares B, Davis C, Schulz W, Juhn Y. Association of delayed asthma diagnosis with asthma exacerbations in children. Journal Of Allergy And Clinical Immunology Global 2025, 4: 100409. PMID: 40008091, PMCID: PMC11851198, DOI: 10.1016/j.jacig.2025.100409.Peer-Reviewed Original ResearchElectronic health recordsDiagnosis of asthmaAsthma diagnosisAsthma exacerbationsRisk of AEPredetermined Asthma CriteriaDiagnosis of childhood asthmaChildhood asthma managementIncreased riskCox proportional hazards modelsIncreased risk of AECare qualityAsthma outcomesHealth recordsProportional hazards modelAsthma managementChildhood asthmaBirth cohortAsthma severityDiagnosis statusIndex dateIdentifying childrenPrimary outcomeNatural language processing algorithmsHazards model
2023
Type 3 Laryngeal Clefts Presenting with Upper Airway Obstruction without Aspiration
Weitzman R, Shah H, Modi V, Maurrasse S. Type 3 Laryngeal Clefts Presenting with Upper Airway Obstruction without Aspiration. The Laryngoscope 2023, 134: 977-980. PMID: 37436152, DOI: 10.1002/lary.30849.Peer-Reviewed Original ResearchUpper airway obstructionLaryngeal cleftAirway obstructionObstructive symptomsEndoscopic repairTracheoesophageal fistulaExercise-induced stridorLaryngeal cleft repairCommon presenting symptomDiagnosis of asthmaSole presenting featureAbsence of dysphagiaAirway symptomsNoisy breathingPresenting featuresPresenting symptomModerate OSABarium swallowClinical featuresSecond patientFirst patientCleft repairDifferential diagnosisPosterior glottisSuspicious features
2020
Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype
Camiolo M, Gauthier M, Kaminski N, Ray A, Wenzel SE. Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype. Journal Of Allergy And Clinical Immunology 2020, 146: 315-324.e7. PMID: 32531372, PMCID: PMC7283064, DOI: 10.1016/j.jaci.2020.05.051.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAngiotensin-Converting Enzyme 2AsthmaBetacoronavirusBiomarkersBronchiBronchoalveolar Lavage FluidCohort StudiesCoronavirus InfectionsCOVID-19EosinophilsFemaleGene Expression ProfilingHumansInterferon Type IInterferon-gammaMaleMiddle AgedPandemicsPeptidyl-Dipeptidase APneumonia, ViralProtein Interaction MappingReceptors, VirusRisk FactorsSARS-CoV-2Severity of Illness IndexT-LymphocytesTranscriptomeUnited StatesConceptsCoronavirus disease 2019Severe coronavirus disease 2019Subset of patientsDisease 2019Risk factorsBronchial epitheliumAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSevere acute respiratory syndrome coronavirus 2Syndrome coronavirus 2 infectionType 2 inflammatory biomarkersAcute respiratory syndrome coronavirus 2Receptor ACE2SARS-CoV-2 receptor ACE2Respiratory syndrome coronavirus 2Asthma inflammatory phenotypesLarge asthma cohortsLower peripheral bloodT cell-activating factorCoronavirus 2 infectionEnzyme 2 (ACE2) expressionHistory of hypertensionDiagnosis of asthmaBronchoalveolar lavage lymphocytesT cell recruitment
2018
Is Adenoidectomy and/or Tonsillectomy a Risk Factor for Allergic Diseases and Asthma in Adulthood?
Yurtsever N, Soyyigit S, Sozener Z, Mungan D, Kose S, Misirligil Z. Is Adenoidectomy and/or Tonsillectomy a Risk Factor for Allergic Diseases and Asthma in Adulthood? Eurasian Journal Of Medicine 2018, 50: 152-155. PMID: 30515033, PMCID: PMC6263232, DOI: 10.5152/eurasianjmed.2018.17182.Peer-Reviewed Original ResearchAllergic rhinitisDrug allergyRisk of asthma in adulthoodVenom allergyFood allergyAllergic diseasesNon-atopic asthmatic patientsRisk of asthmaPatients aged <Asthma in adulthoodDiagnosis of asthmaHistory of adenoidectomyRisk of atopyDisease in adulthoodHistory of atopyHistory of tonsillectomyPathogenesis of asthmaFollowed-upAdenoidectomyAsthmatic patientsTonsillectomyUrticaria-angioedemaRisk ratioRisk factorsPatientsBronchial hyper-responsiveness: a technical update
Borak J, Lefkowitz R, Linde B. Bronchial hyper-responsiveness: a technical update. Occupational Medicine 2018, 68: 519-522. PMID: 30192977, DOI: 10.1093/occmed/kqy122.Peer-Reviewed Original ResearchConceptsMethacholine challenge testingEuropean Respiratory SocietyAmerican Thoracic SocietyDiagnosis of asthmaNew guidelinesAsymptomatic asthmaticsBronchoprovocation testingPD20 valuesATS guidelinesDeep inspirationRespiratory SocietyThoracic SocietyTidal breathingChallenge testingHand searchSystematic reviewClinical testsLongitudinal assessmentBreath holdingAsthmaPD20CliniciansGuidelinesDelivery systemTechnical update
2015
Bronchial hyperresponsiveness
Borak J, Lefkowitz RY. Bronchial hyperresponsiveness. Occupational Medicine 2015, 66: 95-105. PMID: 26590957, DOI: 10.1093/occmed/kqv158.Peer-Reviewed Original ResearchConceptsBronchial hyperresponsivenessBronchoprovocation testingChronic obstructive pulmonary disease patientsVariety of stimuliAssessment of BHRPrevalence of BHRObstructive pulmonary disease patientsPulmonary disease patientsDiagnosis of asthmaStudy of smokersGreat clinical valueBHR testingAirway diseaseLung diseaseDisease patientsClinical valueGeneral populationPathological mechanismsAsthmaHand searchSystematic reviewClinical patientsPatientsWorking populationHyperresponsiveness
2012
Increased Prevalence of Asthma Symptoms in Nigerian Children with Sickle Cell Disease Compared to Children without Sickle Cell Disease
Galadanci N, Liang W, Aliyu M, Jibir B, Karaye I, Inusa B, Vermund S, DeBaun M. Increased Prevalence of Asthma Symptoms in Nigerian Children with Sickle Cell Disease Compared to Children without Sickle Cell Disease. Blood 2012, 120: 4760. DOI: 10.1182/blood.v120.21.4760.4760.Peer-Reviewed Original ResearchAsthma-like symptomsSickle cell diseaseMurtala Mohammed Specialist HospitalMode of deliveryAsthma symptomsCell diseaseGestational agePhysician diagnosisRisk factorsHigh prevalenceParental historyNigerian childrenAmerican Thoracic Society DivisionLung Disease QuestionnaireHistory of coughPrevalence of asthmaDiagnosis of asthmaShortness of breathCase-control study designCause of morbidityDemographic informationRoutine medical careWilcoxon rank sum testChi-square testHigh rateCorrelation between Eosinophil Count and Methacholine Challenge Test in Asymptomatic Subjects
Schwartz N, Grossman A, Levy Y, Schwarz Y. Correlation between Eosinophil Count and Methacholine Challenge Test in Asymptomatic Subjects. Journal Of Asthma 2012, 49: 336-341. PMID: 22715867, DOI: 10.3109/02770903.2012.672613.Peer-Reviewed Original ResearchConceptsMethacholine challenge testNegative methacholine testMethacholine testAirway hyperresponsivenessEosinophil countAsymptomatic subjectsChallenge testSeverity of AHRPositive methacholine challenge testTotal white blood cellsPositive methacholine testPeripheral blood eosinophiliaDiagnosis of asthmaAbsolute eosinophil countTotal eosinophil countFirst-degree relativesWhite blood cellsAsthmatic activityBlood eosinophiliaAbnormal spirometryNeutrophil countMethacholine concentrationPeripheral bloodMedical CenterBlood cells
2010
Lack of Identification of Asthmatic Players in a Youth Soccer League
Weiss P, Bazzy-Asaad A, Tolomeo C. Lack of Identification of Asthmatic Players in a Youth Soccer League. Journal Of Asthma & Allergy Educators 2010, 1: 117-121. DOI: 10.1177/2150129710370703.Peer-Reviewed Original ResearchAsthma action planAsthma exacerbationsUse of bronchodilatorsExercise-induced bronchoconstrictionDiagnosis of asthmaKnowledge of asthmaCause of deathSecondary outcomesAsthma educationAsthma attacksAsthma awarenessMultiple-choice surveyHigh riskGeneral populationAsthmaAge groupsInhalerDescriptive studyLack of awarenessBronchodilatorsYouth soccer playersExacerbationChildrenSoccer playersParent coaches
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