1986
Brief debrisoquin administration to assess central dopaminergic function in children
Riddle M, Shaywitz B, Leckman J, Anderson G, Shaywitz S, Hardin M, Ort S, Cohen D. Brief debrisoquin administration to assess central dopaminergic function in children. Life Sciences 1986, 38: 1041-1048. PMID: 3456480, DOI: 10.1016/0024-3205(86)90239-0.Peer-Reviewed Original ResearchConceptsCentral dopaminergic functionDopaminergic functionHomovanillic acid levelsBehavioral side effectsActive antihypertensive agentDebrisoquin sulfatePHVA levelsAntihypertensive agentsSix-hour periodSide effectsBrief administrationNeuropsychiatric disordersAdministration methodsMarked reductionPeripheral techniquesAcid levelsAdministrationPatientsChildrenDebrisoquinPHVA
1982
Brain catecholamine metabolites and behavior in morphine withdrawal
Swann A, Elsworth J, Charney D, Jablons D, Roth R, Redmond D, Maas J. Brain catecholamine metabolites and behavior in morphine withdrawal. European Journal Of Pharmacology 1982, 86: 167-175. PMID: 6297931, DOI: 10.1016/0014-2999(82)90314-4.Peer-Reviewed Original ResearchConceptsCatecholamine metabolitesMorphine withdrawal behaviorsBeta-receptor bindingWithdrawal behaviorDebrisoquin sulfateAcute treatmentMorphine withdrawalNorepinephrine metaboliteMorphine pelletsWithdrawal signsPlasma levelsBrain 3Noradrenergic hyperactivityReceptor bindingMHPGBrainMetabolitesNaloxoneHVARatsHyperactivity
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