Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss
Jukic AM, Calafat AM, McConnaughey DR, Longnecker MP, Hoppin JA, Weinberg CR, Wilcox AJ, Baird DD, Calafat A, McConnaughey D, Longnecker M, Hoppin J, Weinberg C, Wilcox A, Baird D. Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss. Environmental Health Perspectives 2015, 124: 321-328. PMID: 26161573, PMCID: PMC4786975, DOI: 10.1289/ehp.1408164.Peer-Reviewed Original ResearchConceptsEarly pregnancy lossLuteal phase lengthShort luteal phaseFollicular phase lengthPregnancy lossMonocarboxyoctyl phthalatePhthalate metabolitesLuteal phaseMenstrual cycleDaily first-morning urine specimensFirst morning urine specimensUrinary bisphenol AFuture human studiesHuman chorionic gonadotropinVaginal bleedingDEHP metabolitesUrinary concentrationsHuman ovulationProgesterone metabolitesChorionic gonadotropinUrine specimensDetrimental alterationsHuman studiesAnimal studiesPregnancyPhthalate metabolites and bisphenol-A in association with circulating angiogenic biomarkers across pregnancy
Ferguson K, McElrath T, Cantonwine D, Mukherjee B, Meeker J. Phthalate metabolites and bisphenol-A in association with circulating angiogenic biomarkers across pregnancy. Placenta 2015, 36: 699-703. PMID: 25913709, PMCID: PMC4441857, DOI: 10.1016/j.placenta.2015.04.002.Peer-Reviewed Original ResearchConceptsSFlt-1 to PlGF ratioSFlt-1Biomarkers of angiogenesisPhthalate metabolitesPlGF ratioPlacental developmentSoluble fms-like tyrosine kinase-1Fms-like tyrosine kinase-1Tyrosine kinase-1Placental growth factorUrinary DEHP metabolitesProspective birth cohortAdverse birth outcomesCase-control populationDelivered pretermGestational ageAngiogenic biomarkersExposure to phthalatesUrinary biomarkersDEHP metabolitesBirth outcomesPlasma biomarkersPregnancyPlGFAssociated with decreases
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