2016
[Cardiooncology: Current Aspects of Prevention of Anthracycline Toxicity].
Vasyuk Y, Shkolnik E, Nesterov V, Shkolnik L, Varlan G. [Cardiooncology: Current Aspects of Prevention of Anthracycline Toxicity]. Kardiologiia 2016, 56: 72-79. PMID: 28290807.Peer-Reviewed Original ResearchConceptsPrevention of anthracycline cardiotoxicityMolecular targeted therapySevere side effectsAnthracycline administrationAnthracycline cardiotoxicityChemotherapeutic agentsChemotherapeutic drugsClinical studiesSide effectsAntineoplastic drugsAnthracyclinesCardiotoxicityEarly detectionDrugMyelotoxicityMalignancyEpirubicinThromboembolismTherapyAclarubicinAgentsAlopeciaDaunorubicinDoxorubicinCancer
1999
Hepatic sequestration and modulation of the canalicular transport of the organic cation, daunorubicin, in the rat
Hayes J, Soroka C, Rios‐Velez L, Boyer J. Hepatic sequestration and modulation of the canalicular transport of the organic cation, daunorubicin, in the rat. Hepatology 1999, 29: 483-493. PMID: 9918926, DOI: 10.1002/hep.510290216.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnti-Bacterial AgentsAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1BileBile CanaliculiBiological TransportBucladesineCationsChloroquineDaunorubicinKineticsLiverMacrolidesMaleMitochondrial ProteinsNocodazoleRatsRats, WistarRibosomal ProteinsSaccharomyces cerevisiae ProteinsTaurocholic AcidVerapamilConceptsBiliary excretionCoadministration of verapamilInhibitors of MDR1Rat hepatocyte coupletsBiliary recoveryDose administeredHepatic sequestrationTR- mutant ratsTherapeutic agentsExcretionDaunorubicinPericanalicular regionHepatocyte coupletsCanalicular transportRat liverBafilomycin ATaurocholateRatsIPRLIntracellular acidic compartmentsCellular localizationMicrotubule destabilizerConfocal microscopyIRHCPattern of distribution
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