2024
Nephron-Sparing Surgery for Upper Urinary Tract Urothelial Carcinoma
Kim S, Savul I, Lerner S. Nephron-Sparing Surgery for Upper Urinary Tract Urothelial Carcinoma. Journal Of Urologic Oncology 2024, 22: 68-77. DOI: 10.22465/juo.244600180009.Peer-Reviewed Original ResearchUpper tract urothelial carcinomaNephron-sparing surgeryRadical nephroureterectomyUrothelial carcinomaSurgical management of upper tract urothelial carcinomaEffect of nephron-sparing surgeryRenal pelvisUpper urinary tract urothelial carcinomaManagement of upper tract urothelial carcinomaUrinary tract urothelial carcinomaIntact kidneysMinimally invasive surgical approachEvasion of immune destructionLow tumor burdenRenal function deteriorationRisk of recurrenceInvasive surgical approachRobotic-assisted techniquesOncological outcomesTumor burdenIpsilateral ureterUreteral reimplantationDistal ureterSurgical managementAdjuvant administration
2022
Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis
Kwon H, Yu K, Cahill S, Alder K, Dussik C, Kim S, Sharma L, Back J, Oh I, Lee F. Concurrent targeting of glycolysis in bacteria and host cell inflammation in septic arthritis. EMBO Molecular Medicine 2022, 14: emmm202115284. PMID: 36354099, PMCID: PMC9728052, DOI: 10.15252/emmm.202115284.Peer-Reviewed Original ResearchConceptsDrug dimethyl fumarateSeptic arthritisIntracellular MRSABacterial joint infectionSoft tissue infectionsAnti-inflammatory effectsInfection-associated inflammationNovel therapeutic paradigmContext of infectionConventional antibiotic treatmentHost cellsAdjuvant administrationSurgical treatmentTissue infectionsClinical symptomsInflammatory machineryJoint infectionBacterial burdenAntibiotic treatmentCell inflammationHost inflammationArthritisInflammationIntraarticular inflammationTherapeutic paradigm
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