2019
Clinical impact of intraoperative hyperlactatemia during craniotomy
Romano D, Deiner S, Cherukuri A, Boateng B, Shrivastava R, Mocco J, Hadjipanayis C, Yong R, Kellner C, Yaeger K, Lin H, Brallier J. Clinical impact of intraoperative hyperlactatemia during craniotomy. PLOS ONE 2019, 14: e0224016. PMID: 31647826, PMCID: PMC6812741, DOI: 10.1371/journal.pone.0224016.Peer-Reviewed Original ResearchConceptsElevated lactateNeurological deficitsSerum lactateAssociated with new postoperative neurological deficitsCritically ill septic shock patientsCraniotomy patientsEarly due to futilityElevated serum lactate levelsAssociated with poor outcomesLactate levelsAssociated with neurological complicationsPostoperative neurological deficitsHospital length of staySeptic shock patientsSerum lactate levelsPostoperative myocardial infarctionDay of surgeryElevated lactate levelsArterial lactate valuesElective craniotomy patientsLength of stayCardiac surgeryTroponin valuesSystemic complicationsDay mortality
2017
Elevated Intraoperative Serum Lactate During Craniotomy Is Associated With New Neurological Deficit and Longer Length of Stay
Brallier J, Dalal P, McCormick P, Lin H, Deiner S. Elevated Intraoperative Serum Lactate During Craniotomy Is Associated With New Neurological Deficit and Longer Length of Stay. Journal Of Neurosurgical Anesthesiology 2017, 29: 388-392. PMID: 27438799, DOI: 10.1097/ana.0000000000000332.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedCerebrovascular CirculationCohort StudiesCraniotomyFemaleHumansIntraoperative ComplicationsLactic AcidLength of StayMaleMiddle AgedMyocardial InfarctionNervous System DiseasesNeurosurgical ProceduresPerfusionPostoperative ComplicationsRetrospective StudiesRisk FactorsSurvival AnalysisTreatment OutcomeConceptsAssociated with new neurological deficitsNew neurological deficitsSerum lactateNeurological deficitsAssociated with systemic complicationsElevated serum lactateSerum lactate levelsRetrospective cohort studySurgical decision-makingAssociated with hypoperfusionLonger length of stayLength of stayInadequate blood supplySystemic complicationsSystemic hypoperfusionFluid resuscitationElevated lactateProspective studyClinical impactCraniotomy casesLonger lengthGlobal hypoperfusionSurgical retractionCohort studyCraniotomy patients
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