The role of hyperosmotic stress in inflammation and disease
Brocker C, Thompson DC, Vasiliou V. The role of hyperosmotic stress in inflammation and disease. BioMolecular Concepts 2012, 3: 345-364. PMID: 22977648, PMCID: PMC3438915, DOI: 10.1515/bmc-2012-0001.Peer-Reviewed Original ResearchHyperosmotic stressNon-renal tissuesCell cycle arrestHigh extracellular osmolarityOsmolyte synthesisCytoskeletal rearrangementsRegulatory pathwaysMitochondrial depolarizationShock proteinsHyperosmotic conditionsHuman diseasesCell shrinkageDNA damageMammalian kidneyCycle arrestInner medullary regionProtein carbonylationCytoprotective mechanismsExtracellular osmolarityConcentrating mechanismAntioxidant enzymesAdaptive mechanismsPhysiological conditionsPathological consequencesOxidative stress
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply