2024
Predicting Hypoglycemia and Hyperglycemia Risk During and After Activity for Adolescents with Type 1 Diabetes
Bergford S, Riddell M, Gal R, Patton S, Clements M, Sherr J, Calhoun P. Predicting Hypoglycemia and Hyperglycemia Risk During and After Activity for Adolescents with Type 1 Diabetes. Diabetes Technology & Therapeutics 2024, 26: 728-738. PMID: 38669475, DOI: 10.1089/dia.2024.0061.Peer-Reviewed Original ResearchRepeated measures logistic regressionPhysically active adolescentsHyperglycemia riskType 1 diabetesMeasures logistic regressionComposite riskAcute glucose responseGlucose rateWearing continuous glucose monitoringContinuous glucose monitoringReceiver operating characteristic curveArea under the receiver operating characteristic curveRisk of hypoglycemiaLogistic regressionActive adolescentsHbA1c levelsActivity startExerciseAdolescentsRiskCharacteristic curveHypoglycemiaGlucose responseHyperglycemiaT1D
2022
Six-year absolute invasive disease-free survival benefit of adding adjuvant pertuzumab to trastuzumab and chemotherapy for patients with early HER2-positive breast cancer: A Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of the APHINITY (BIG 4-11) trial
Gelber RD, Wang XV, Cole BF, Cameron D, Cardoso F, Tjan-Heijnen V, Krop I, Loi S, Salgado R, Kiermaier A, Frank E, Fumagalli D, Caballero C, de Azambuja E, Procter M, Clark E, Restuccia E, Heeson S, Bines J, Loibl S, Piccart-Gebhart M, Committee and Investigators A. Six-year absolute invasive disease-free survival benefit of adding adjuvant pertuzumab to trastuzumab and chemotherapy for patients with early HER2-positive breast cancer: A Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of the APHINITY (BIG 4-11) trial. European Journal Of Cancer 2022, 166: 219-228. PMID: 35313167, DOI: 10.1016/j.ejca.2022.01.031.Peer-Reviewed Original ResearchConceptsSubpopulation treatment effect pattern plotInvasive disease-free survivalComposite risk scoreAdjuvant pertuzumabAPHINITY trialTIL percentageBreast cancerRisk scoreSubpopulation treatment effect pattern plot analysisEarly HER2-positive breast cancerDisease-free survival benefitHER2-positive breast cancerTreatment effectsNode-positive cohortDisease-free survivalEarly breast cancerNodal statusSurvival benefitLymphocyte percentagePatient subpopulationsComposite riskPatientsCovariates of interestChemotherapyPertuzumab
2020
Evaluation of a Risk Stratification Model Using Preoperative and Intraoperative Data for Major Morbidity or Mortality After Cardiac Surgical Treatment
Durant TJS, Jean RA, Huang C, Coppi A, Schulz WL, Geirsson A, Krumholz HM. Evaluation of a Risk Stratification Model Using Preoperative and Intraoperative Data for Major Morbidity or Mortality After Cardiac Surgical Treatment. JAMA Network Open 2020, 3: e2028361. PMID: 33284333, PMCID: PMC11841993, DOI: 10.1001/jamanetworkopen.2020.28361.Peer-Reviewed Original Research
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