Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy
Kang Y, Xu B, Shi S, Zhou X, Chen P, Liu L, Li Y, Leng Y, Lv J, Zhu L, Zhang H. Mesangial C3 Deposition, Complement-Associated Variant, and Disease Progression in IgA Nephropathy. Clinical Journal Of The American Society Of Nephrology 2023, 18: 1583-1591. PMID: 37651123, PMCID: PMC10723908, DOI: 10.2215/cjn.0000000000000290.Peer-Reviewed Original ResearchConceptsMesangial C3 depositionGenome-wide association studiesIgA nephropathyComplement factor HC3 depositionGenotype-phenotype correlationIntensity of C3 depositionAssociation studiesLong-term kidney outcomesSusceptibility variantsProgression of IgA nephropathySevere clinical phenotypeKaplan-Meier analysisDeposition of IgAIgA nephropathy cohortIgA nephropathy progressionComplement component 3Chi-square testPrimary GNClinical phenotypeKidney outcomesFactor HGenotypesChinese patientsComplement regulators
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply