2024
Complement factor H in molecular regulation of angiogenesis
Li J, Wang K, Starodubtseva M, Nadyrov E, Kapron C, Hoh J, Liu J. Complement factor H in molecular regulation of angiogenesis. Medical Review 2024, 4: 452-466. PMID: 39444793, PMCID: PMC11495524, DOI: 10.1515/mr-2023-0048.Peer-Reviewed Original ResearchComplement factor HComplement factor H geneAge-related macular degenerationComplement factor H proteinFactor HComplement activation fragmentsC-reactive proteinAnti-angiogenic effectsEndothelial heparan sulfateChoroidal neovascularizationMacular degenerationRegulation of angiogenesisMolecular regulation of angiogenesisDeficient miceComplement 3aMembrane attack complexComplement 5aPro-angiogenic eventsAngiogenesis-related diseasesCFH expressionPro-angiogenic capacityAlternative pathwayTherapeutic potentialComplement systemBlood vessels
2019
Complement factor H gene polymorphisms and vivax malaria associated thrombotic microangiopathy.
Agrawal P, Kumar A, Parwaiz A, Rawat A, Tiewsoh K, Nada R. Complement factor H gene polymorphisms and vivax malaria associated thrombotic microangiopathy. Saudi Journal Of Kidney Diseases And Transplantation 2019, 30: 540-544. PMID: 31031394, DOI: 10.4103/1319-2442.256865.Peer-Reviewed Original ResearchConceptsAcute kidney injuryComplement factor HThrombotic microangiopathyAlternative complement pathwayVivax malariaCFH gene polymorphismDysregulated alternate complement pathwayComplement factor H geneDevelopment of thrombotic microangiopathyCases of malariaMechanism of injuryKidney injuryExon 9Exon 7MalariaSingle-nucleotide polymorphismsMicroangiopathyVivaxComplement pathwayMortality rateFactor HPatientsInjuryPolymorphismComplement
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