2025
Red blood cell casts on kidney biopsy and progression of IgA nephropathy
Yao Y, Tang C, Shi S, Chen P, Zhou X, Lv J, Liu L, Zhang H. Red blood cell casts on kidney biopsy and progression of IgA nephropathy. Nephrology Dialysis Transplantation 2025, gfaf023. PMID: 39909472, DOI: 10.1093/ndt/gfaf023.Peer-Reviewed Original ResearchComposite kidney endpointRed blood cell castsMedian Follow-UpImmunosuppressive therapyKidney endpointsCell castsFollow-upIgA nephropathyKidney diseaseProgression of IgA nephropathyDisease progression of patientsCox regression analysisEnd stage kidney diseaseKidney disease progressionAcute active lesionsStage kidney diseaseProgression of patientsRenal prognosisCrescentic lesionsDeath due to kidney diseaseKidney biopsyKidney outcomesUnivariate analysisActive lesionsMultivariate analysis
2024
Prognosis of IgA nephropathy patient with proteinuria remission by supportive therapy: cohort from screening failed Chinese patients in TESTING study
Guo Y, Shi S, Zhao J, Wang C, Liu Z, Fu S, Chen N, Li G, Wang L, Ni Z, Zhang H, Lai L, Lv J, Zhang H. Prognosis of IgA nephropathy patient with proteinuria remission by supportive therapy: cohort from screening failed Chinese patients in TESTING study. Renal Failure 2024, 46: 2398826. PMID: 39248402, PMCID: PMC11385640, DOI: 10.1080/0886022x.2024.2398826.Peer-Reviewed Original ResearchConceptsRelapse of proteinuriaImmunosuppressive therapyComposite kidney outcomeKaplan-Meier analysisProteinuria remissionKidney outcomesFollow-upSupportive therapyKidney outcomes of patientsLong-term kidney outcomesRenin-angiotensin system blockersComposite kidney endpointRemission of proteinuriaOutcomes of patientsLong-term prognosisRun-in phaseIgA nephropathy patientsStages of follow-upIntensive supportive therapyEarly stage of follow-upPersistent remissionDialysis of patientsKidney survivalRenal transplantationKidney endpointsEffects of Sodium-Glucose Cotransporter-2 Inhibitors on Kidney Outcomes across Baseline Cardiovascular-Kidney-Metabolic Conditions
Siddiqi T, Cherney D, Siddiqui H, Jafar T, Januzzi J, Khan M, Levin A, Marx N, Rangaswami J, Testani J, Usman M, Wanner C, Zannad F, Butler J. Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Kidney Outcomes across Baseline Cardiovascular-Kidney-Metabolic Conditions. Journal Of The American Society Of Nephrology 2024, 36: 242-255. PMID: 39230974, PMCID: PMC11801753, DOI: 10.1681/asn.0000000000000491.Peer-Reviewed Original ResearchSodium-glucose cotransporter-2 inhibitorsType 2 diabetes mellitusChronic kidney diseaseEffects of sodium-glucose cotransporter-2 inhibitorsComposite kidney endpointCotransporter-2 inhibitorsKidney outcomesHeart failureKidney diseaseKidney endpointsHazard ratioDoubling of serum creatinineCombination of heart failureSustained doubling of serum creatininePlacebo-controlled trialReduced ejection fractionBaseline heart failureConfidence intervalsRandom-effects modelAlbuminuria progressionEjection fractionSerum creatinineReview ManagerMellitusPatients
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