2021
Evaluation of Trials Comparing Single-Enantiomer Drugs to Their Racemic Precursors
Long AS, Zhang AD, Meyer CE, Egilman AC, Ross JS, Wallach JD. Evaluation of Trials Comparing Single-Enantiomer Drugs to Their Racemic Precursors. JAMA Network Open 2021, 4: e215731. PMID: 33956134, PMCID: PMC8103227, DOI: 10.1001/jamanetworkopen.2021.5731.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsSafety end pointEnd pointClinical trialsDrug pairsPrimary end point resultsEnd point resultsImproved efficacyEfficacy end pointCochrane Central RegistrySeparate end pointsSingle-enantiomer drugsSingle enantiomer formulationPrimary efficacySecondary efficacyControlled TrialsOvid EmbaseOvid MEDLINESuperior efficacyDrug AdministrationCentral RegistrySystematic reviewMore efficacyTrialsRacemic drugs
2014
Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort
Liew Z, Ritz B, von Ehrenstein OS, Bech BH, Nohr EA, Fei C, Bossi R, Henriksen TB, Bonefeld-Jørgensen EC, Olsen J. Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort. Environmental Health Perspectives 2014, 123: 367-373. PMID: 25616253, PMCID: PMC4383573, DOI: 10.1289/ehp.1408412.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderDanish National Birth CohortNational Birth CohortDeficit/hyperactivity disorderPrenatal exposureRisk ratioChildhood autismBirth cohortDanish National Hospital RegistryDanish Psychiatric Central RegistryNested Case-Control StudyRisk of ADHDNational Hospital RegistryPrenatal PFAS exposureHyperactivity disorderCase-control studyMother-child pairsPerfluoroalkyl substancesConsistent evidenceHospital registryProspective studyPlasma levelsNeurobehavioral problemsPFAS exposureCentral Registry
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply