2025
512 Predicting outcomes of lifestyle and stress reduction interventions for obesity with DNA methylation and psychological measures
Harvanek Z, Li C, Xu K, Jastreboff A, Sinha R. 512 Predicting outcomes of lifestyle and stress reduction interventions for obesity with DNA methylation and psychological measures. Journal Of Clinical And Translational Science 2025, 9: 150-150. PMCID: PMC12050514, DOI: 10.1017/cts.2024.1093.Peer-Reviewed Original ResearchStress reduction interventionsReduction interventionsLinear mixed modelsActivity counselingLifestyle interventionPsychological measuresObesity-related outcomesIntervention control groupBaseline psychological measuresEffects of lifestyleYears of obesityRisk of comorbiditiesEpigenetic age accelerationNumerous health issuesAssociated with obesityPost-interventionRandomized-controlled trialsReduce obesityHealth issuesYear Follow-UpDecreased riskHOMA-IRLifestylePsychological factorsIntervention
2018
Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention: A Randomized Pilot Study
Jastreboff AM, Chaplin TM, Finnie S, Savoye M, Stults-Kolehmainen M, Silverman WK, Sinha R. Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention: A Randomized Pilot Study. The Journal Of Pediatrics 2018, 202: 136-142.e1. PMID: 30241766, PMCID: PMC6203652, DOI: 10.1016/j.jpeds.2018.07.011.Peer-Reviewed Original ResearchConceptsChildhood obesityChild body mass indexGroup interventionPhysical activity counselingRandomized pilot studyBody mass indexChildhood obesity riskControl group interventionEarly childhood obesityStress interventionsActivity counselingMass indexObesity riskPhysical activityTherapeutic mechanismObesityGroup attendanceRisk 2Pilot studyInterventionSignificant increaseLow-income parentsGreater improvementRiskParent-child dyads
2015
Comparative Effectiveness of Childhood Obesity Interventions in Pediatric Primary Care: A Cluster-Randomized Clinical Trial
Taveras EM, Marshall R, Kleinman KP, Gillman MW, Hacker K, Horan CM, Smith RL, Price S, Sharifi M, Rifas-Shiman SL, Simon SR. Comparative Effectiveness of Childhood Obesity Interventions in Pediatric Primary Care: A Cluster-Randomized Clinical Trial. JAMA Pediatrics 2015, 169: 535-542. PMID: 25895016, DOI: 10.1001/jamapediatrics.2015.0182.Peer-Reviewed Original ResearchConceptsClinical decision supportQuality of carePediatric cliniciansChildhood obesityClinical trialsHEDIS measuresCoaching armInformation Set (HEDIS) performance measuresImproved body mass indexComputerized clinical decision supportMean patient ageUsual care armPhysical activity counselingBody mass indexHealthcare Effectiveness DataPrimary care settingPediatric primary careChildhood obesity interventionsPrimary care practicesFamily coachingAge-associated changesCare armRandomization armActivity counselingBehavior change
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