Impact of Age and Sex on Coronary Flow Reserve and Microvascular Function in Patients with ANOCA
Kostantinis S, Castro G, Latif N, Cigarroa N, Kunnirickal S, Odanovic N, Shah S. Impact of Age and Sex on Coronary Flow Reserve and Microvascular Function in Patients with ANOCA. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 103989. DOI: 10.1016/j.jscai.2025.103989.Peer-Reviewed Original ResearchCoronary flow reserveCoronary microvascular functionMicrovascular functionImpact of ageMicrocirculatory resistanceInvasive coronary function testingFlow reserveCoronary function testingAssessment of coronary flow reserveNonobstructive coronary arteriesAssociated with progressive decreasesHyperemic mean transit timeHyperemic TmnAssociation of ageCoronary physiology indicesAcetylcholine provocationMean transit timeVasoreactivity testingConsecutive patientsBolus thermodilutionSex-stratified analysesMultivariate regression modelSubgroup analysisAge-related impairmentANOCA
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