2025
Aortic valve calcium as a novel risk marker for kidney function deterioration: The MESA study
Abdollahi A, Sani M, Shabani M, Matuck B, Blaha M, Wu C, Ambale-Venkatesh B, Budoff M, Strom J, Rotter J, Post W, Blumenthal R, Bluemke D, Ghahramani N, Lima J, Whelton S. Aortic valve calcium as a novel risk marker for kidney function deterioration: The MESA study. European Journal Of Internal Medicine 2025, 136: 49-55. PMID: 40263084, DOI: 10.1016/j.ejim.2025.03.037.Peer-Reviewed Original ResearchConceptsMulti-Ethnic Study of AtherosclerosisRisk of incident chronic kidney diseaseIncident chronic kidney diseaseAortic valve calciumInternational Classification of DiseasesChronic kidney diseaseCardiac CT scansAdjusted Cox proportional hazards regression modelsMultivariable adjusted Cox proportional hazards regression modelsParticipants free of chronic kidney diseaseCardiovascular diseaseMulti-Ethnic Study of Atherosclerosis studyValve calciumCT scanCVD risk factorsHistory of cardiovascular diseaseCategorized as 0Higher risk of incident CKDFree of chronic kidney diseaseAssociated with increased risk of mortalityMulti-Ethnic StudyAtherosclerotic CVD risk factorsMulti-ethnic cohortAPOE-e4 genotypeClassification of diseases
2021
Long-Term Prognostic Implications and Role of Further Testing in Adults Aged ≤55 Years With a Coronary Calcium Score of Zero (from the Multi-Ethnic Study of Atherosclerosis)
Cainzos-Achirica M, Acquah I, Dardari Z, Mszar R, Greenland P, Blankstein R, Bittencourt M, Rajagopalan S, Al-Kindi S, Polak J, Blumenthal R, Blaha M, Nasir K. Long-Term Prognostic Implications and Role of Further Testing in Adults Aged ≤55 Years With a Coronary Calcium Score of Zero (from the Multi-Ethnic Study of Atherosclerosis). The American Journal Of Cardiology 2021, 161: 26-35. PMID: 34794615, PMCID: PMC8607758, DOI: 10.1016/j.amjcard.2021.08.067.Peer-Reviewed Original ResearchConceptsAortic valve calciumCoronary artery calciumCoronary calcium scoreLong-term prognosisCardiovascular diseaseICA-IMTCoronary calcium score of zeroCalcium score of zeroHigh-sensitivity C-reactive protein levelsLong-term prognostic significanceC-reactive protein levelsMedian Follow-UpMulti-Ethnic StudyMitral annular calciumEvent ratesPremature family historyThoracic aortic calciumScore of zeroCardiovascular disease eventsAnkle-brachial indexValve calciumAnnular calciumPrognostic significancePrognostic implicationsAortic calcium
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