2024
Primary Tumor Characteristics as Biomarkers of Immunotherapy Response in Advanced Melanoma: A Retrospective Cohort Study
Goodman R, Jung S, Fletcher K, Burnette H, Mohyuddin I, Irlmeier R, Ye F, Johnson D. Primary Tumor Characteristics as Biomarkers of Immunotherapy Response in Advanced Melanoma: A Retrospective Cohort Study. Cancers 2024, 16: 2355. PMID: 39001417, PMCID: PMC11240575, DOI: 10.3390/cancers16132355.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsRetrospective cohort studyCutaneous melanomaAssociated with responseMelanoma patientsImmunotherapy responseTreated with immune checkpoint inhibitorsCohort studySingle-center retrospective cohort studyAssociated with shorter PFSAnti-PD-1 monotherapyAssociated with inferior outcomesBiomarkers of immunotherapy responsePrimary tumor characteristicsPrimary tumor featuresAdvanced melanoma patientsResponse to immunotherapySingle-center designCheckpoint inhibitorsShorter PFSAdvanced melanomaTumor characteristicsPrimary melanomaMutation statusMetastatic stage
2022
Identification of tumour immune infiltration-associated snoRNAs (TIIsno) for predicting prognosis and immune landscape in patients with colon cancer via a TIIsno score model
Cai C, Peng Y, Shen E, Wan R, Gao L, Gao Y, Zhou Y, Huang Q, Chen Y, Liu P, Guo C, Feng Z, Zhang X, Liu Y, Shen H, Zeng S, Han Y. Identification of tumour immune infiltration-associated snoRNAs (TIIsno) for predicting prognosis and immune landscape in patients with colon cancer via a TIIsno score model. EBioMedicine 2022, 76: 103866. PMID: 35144219, PMCID: PMC8844792, DOI: 10.1016/j.ebiom.2022.103866.Peer-Reviewed Original ResearchConceptsImmune cellsColon cancerImmune landscapeTumor microenvironmentImmune checkpoint expression levelsTumor-infiltrating immune cellsBiomarkers of immunotherapy responseCentral Universities of Central South UniversityNational Key R & D ProgramTumor-related deathColon cancer cell linesCell linesNatural Science Foundation of Hunan ProvinceImmune cell linesMSI-H patientsCentral South UniversityPrognosis of CC patientsImmunotherapy efficacyCancer cell linesImmunotherapy responseImmune scoreInfiltration levelsPredicting PrognosisScore modelCC patients
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