2024
A mosquito salivary protein-driven influx of myeloid cells facilitates flavivirus transmission
Wang Z, Nie K, Liang Y, Niu J, Yu X, Zhang O, Liu L, Shi X, Wang Y, Feng X, Zhu Y, Wang P, Cheng G. A mosquito salivary protein-driven influx of myeloid cells facilitates flavivirus transmission. The EMBO Journal 2024, 43: 1690-1721. PMID: 38378891, PMCID: PMC11066113, DOI: 10.1038/s44318-024-00056-x.Peer-Reviewed Original ResearchMyeloid cellsExpression of neutrophil chemoattractantsViral transmissionInflux of myeloid cellsMosquito bite siteSalivary componentsInflux of neutrophilsSkin-resident macrophagesPotential prophylactic targetsFlavivirus transmissionNF-kB signalingMechanism of actionProphylactic targetsSystemic disseminationRecruits proteinsSalivary factorsLocal infectionNeutrophil chemoattractantMammalian hostsEfficient viral transmissionPhytochemical resveratrolDengue virusBite siteTransmission of ZikaProtein
2018
Inferring the risk factors behind the geographical spread and transmission of Zika in the Americas
Gardner LM, Bóta A, Gangavarapu K, Kraemer MUG, Grubaugh ND. Inferring the risk factors behind the geographical spread and transmission of Zika in the Americas. PLOS Neglected Tropical Diseases 2018, 12: e0006194. PMID: 29346387, PMCID: PMC5790294, DOI: 10.1371/journal.pntd.0006194.Peer-Reviewed Original ResearchConceptsZika virus transmissionRisk factorsZika virusLocal transmissionVirus transmissionZika virus epidemicTransmission of ZikaRegional socioeconomic factorsEpidemiological elementsIncidence rateEpidemiological dataZika casesRisk profileInfection modelRisk of spreadVirus epidemicLocal vector controlSocioeconomic factorsVector-Borne PathogensVirusEpidemicHealth risks
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