Tetraspanin protein CD9 interacts with metalloprotease CD10 and enhances its release via exosomes
Mazurov D, Barbashova L, Filatov A. Tetraspanin protein CD9 interacts with metalloprotease CD10 and enhances its release via exosomes. The FEBS Journal 2013, 280: 1200-1213. PMID: 23289620, DOI: 10.1111/febs.12110.Peer-Reviewed Original ResearchConceptsPeptidase activityPre-B cellsTetraspanin CD9Cytoplasmic C-terminal domainC-terminal domainTetraspanin protein CD9C-terminal tailSite-directed mutagenesisShort hairpin RNA knockdownTransmembrane domain 4CD9 expressionMaturation of pre-B cellsLevel of CD10 expressionExtracellular matrix microenvironmentTetraspanin webCD10-positive cellsLevels of CD10Molecular partnersIntracellular proteinsMigration of B cellsStable expressionTetraspaninDomain 4Associated with CD9CD10 expression
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