2021
Optimization of repeat plerixafor dosing for autologous peripheral blood stem-cell collection
Gupta GK, Perreault S, Seropian SE, Tormey CA, Hendrickson JE. Optimization of repeat plerixafor dosing for autologous peripheral blood stem-cell collection. Transfusion And Apheresis Science 2021, 60: 103069. PMID: 33546988, DOI: 10.1016/j.transci.2021.103069.Peer-Reviewed Original ResearchConceptsPeripheral blood CD34Day 1Blood CD34Autologous peripheral blood stem cell collectionAutologous peripheral blood stem cell mobilizationPeripheral blood stem cell mobilizationPeripheral blood stem cell collectionBlood stem cell mobilizationBlood stem cell collectionDose of plerixaforAddition of plerixaforPercent of casesStem cell collectionStem cell mobilizationQuality improvement projectAdult patientsRepeat dosingPeripheral CD34Multiple myelomaCell mobilizationCollection goalGroup 2Retrospective evaluationGroup 1Patient experience
2020
Optimization of Plerixafor Utilization Based on Peripheral Blood CD34+ Count for Autologous Peripheral Blood Stem-Cell Collection
Gupta G, Perreault S, Seropian S, Tormey C, Hendrickson J. Optimization of Plerixafor Utilization Based on Peripheral Blood CD34+ Count for Autologous Peripheral Blood Stem-Cell Collection. Blood 2020, 136: 41. DOI: 10.1182/blood-2020-140171.Peer-Reviewed Original ResearchPeripheral blood CD34Second doseGroup 2Group 1Peripheral CD34Multiple myelomaPlerixafor groupFirst dayAutologous peripheral blood stem cell collectionPeripheral blood stem cell collectionBlood CD34C chemokine receptor type 4Autologous stem cell mobilizationBlood stem cell collectionTertiary care medical centerChemokine receptor type 4Dose of plerixaforReceptor type 4Stem cell collectionStem cell mobilizationAdult patientsFilgrastim treatmentPhysician's discretionCollection goalRetrospective analysis
2016
Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice
Saito Y, Ellegast JM, Rafiei A, Song Y, Kull D, Heikenwalder M, Rongvaux A, Halene S, Flavell RA, Manz MG. Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice. Blood 2016, 128: 1829-1833. PMID: 27543436, PMCID: PMC5054696, DOI: 10.1182/blood-2015-10-676452.Peer-Reviewed Original ResearchConceptsPeripheral blood CD34Higher engraftment levelsColony-stimulating factorBone marrowEngraftment levelsHuman hemato-lymphoid systemBlood CD34Granulocyte-macrophage colony-stimulating factorAdult recipient miceNonobese diabetic/Macrophage colony-stimulating factorSignal regulatory protein αCord blood-derived CD34Blood-derived CD34Regulatory protein αMISTRG miceAdult recipientsRecipient miceDiabetic/T cellsNonhematopoietic organsMyeloid cellsImmune systemCD34Mice
1998
High-dose chemotherapy followed by reinfusion of selected CD34+ peripheral blood cells in patients with poor-prognosis breast cancer: a randomized multicentre study
Chabannon C, Cornetta K, Lotz J, Rosenfeld C, Shlomchik M, Yanovitch S, Marolleau J, Sledge G, Novakovitch G, Srour E, Burtness B, Camerlo J, Gravis G, Lee-Fischer J, Faucher C, Chabbert I, Krause D, Maraninchi D, Mills B, Kunkel L, Oldham F, Blaise D, Viens P. High-dose chemotherapy followed by reinfusion of selected CD34+ peripheral blood cells in patients with poor-prognosis breast cancer: a randomized multicentre study. British Journal Of Cancer 1998, 78: 913-921. PMID: 9764583, PMCID: PMC2063121, DOI: 10.1038/bjc.1998.601.Peer-Reviewed Original ResearchConceptsPoor prognosis breast cancerHigh-dose chemotherapyHaematopoietic recoveryBreast cancerRecombinant human granulocyte colony-stimulating factorBlood cellsRandomized multicentre studyGranulocyte colony-stimulating factorHuman granulocyte colony-stimulating factorPeripheral blood cellsPeripheral blood CD34Peripheral blood progenitorsColony-stimulating factorMobilized blood cellsEpithelial tumor cellsEligible patientsStudy armsMulticentre studyPeripheral bloodConventional chemotherapyStudy groupPatientsChemotherapyBlood CD34CD34
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