The impact of implementing a non-invasive preimplantation genetic testing for aneuploidies (niPGT-A) embryo culture protocol on embryo viability and clinical outcomes
Sakkas D, Navarro-Sánchez L, Ardestani G, Barroso G, Bisioli C, Boynukalin K, Cimadomo D, Frantz N, Kopcow L, Andrade G, Ozturk B, Rienzi L, Weiser A, Valbuena D, Simón C, Rubio C. The impact of implementing a non-invasive preimplantation genetic testing for aneuploidies (niPGT-A) embryo culture protocol on embryo viability and clinical outcomes. Human Reproduction 2024, 39: 1952-1959. PMID: 39059790, DOI: 10.1093/humrep/deae156.Peer-Reviewed Original ResearchNon-invasive preimplantation genetic testingEmbryo culture protocolsNiPGT-ADay of biopsyPreimplantation genetic testingPGT-APregnancy outcomesPregnancy rateIVF clinicsClinical outcomesControl groupStudy groupGenetic testingReproductive outcomesConcordance rateDay 6Clinical pregnancy rateOverall pregnancy outcomeClinical reproductive outcomesBiopsy stepBlastocyst mediumBlastocyst viabilityBlastocyst developmentCulture protocolMiscarriage rateP-533 Impact on clinical outcomes of day-6 extended culture and reduced culture media volume applied to non-invasive PGT-A
LLuesa C, Navarro-Sánchez L, Ardestani G, Barroso G, Bisioli C, Boynukalin K, Cimadomo D, Andrade G, Valbuena D, Simon-Valles C, Sakkas D. P-533 Impact on clinical outcomes of day-6 extended culture and reduced culture media volume applied to non-invasive PGT-A. Human Reproduction 2024, 39: deae108.873. DOI: 10.1093/humrep/deae108.873.Peer-Reviewed Original ResearchNon-invasive PGT-ACell-free DNAPGT-ASingle embryo transferClinical outcomesDay 5Pregnancy rateStudy groupNiPGT-AConcordance ratePregnancy outcomesDay 6Control groupCell-free DNA resultsDay 5 blastocystsDay 6 blastocystsClinical pregnancy rateDay of biopsyOverall pregnancy outcomeEmbryo culture protocolsBiopsy stepPGT-A.Euploidy rateBlastocyst viabilityBlastocyst quality
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