Developmental therapeutics and the acquired immunodeficiency syndrome.
DEVITA V, BRODER S, FAUCI A, KOVACS J, CHABNER B. Developmental therapeutics and the acquired immunodeficiency syndrome. Annals Of Internal Medicine 1987, 106: 568-81. PMID: 2435201, DOI: 10.7326/0003-4819-106-4-568.Peer-Reviewed Original ResearchConceptsHuman T-lymphotropic virus type IIIPotential screening targetsTreatment of AIDST4 subsetOverwhelming infectionImmunodeficiency syndromeOpportunistic infectionsDevelopmental therapeuticsImmune competenceAntiviral drugsViral DNA polymeraseScreening targetsType IIIInfectionAIDSViral integrationDrugsSpecific targetsEncouraging resultsPatientsSyndromeLymphocytesT-Lymphocyte Subsets in Renal Allograft Recipients Treated with Cyclosporine and Azathioprine
SUMPIO B, DWYER J, FLYE M. T-Lymphocyte Subsets in Renal Allograft Recipients Treated with Cyclosporine and Azathioprine. Annals Of Surgery 1987, 205: 49-53. PMID: 3541801, PMCID: PMC1492880, DOI: 10.1097/00000658-198701000-00009.Peer-Reviewed Original ResearchConceptsT4/T8 ratioRenal allograft recipientsT cell subsetsAntithymocyte globulinAllograft recipientsT8 ratioImmunosuppressive agentsPlasma levelsT lymphocytesNormal T4/T8 ratioDifferent immunosuppression protocolsT lymphocyte subsetsT4/T8Monoclonal antibody OKT3Cytomegalovirus titersImmunosuppression protocolsT4 subsetAntibody OKT3CyclosporinePatientsAzathioprineOnly azathioprineSelective ablationPrednisoneOKT3
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