2025
Tethered to survive: Mitotic transcription secures faithful inheritance of extrachromosomal DNA
Jin X, Verhaak R. Tethered to survive: Mitotic transcription secures faithful inheritance of extrachromosomal DNA. Molecular Cell 2025, 85: 2813-2815. PMID: 40780177, DOI: 10.1016/j.molcel.2025.07.010.Peer-Reviewed Original Research
2021
An active tethering mechanism controls the fate of vesicles
An SJ, Rivera-Molina F, Anneken A, Xi Z, McNellis B, Polejaev VI, Toomre D. An active tethering mechanism controls the fate of vesicles. Nature Communications 2021, 12: 5434. PMID: 34521845, PMCID: PMC8440521, DOI: 10.1038/s41467-021-25465-y.Peer-Reviewed Original ResearchConceptsArtificial tetherFull fusionOptogenetic controlExocyst complexExocyst functionVesicle tethersMembrane mergerTethering mechanismTarget membraneIntracellular fusionPlasma membraneMode of fusionVesicle fusionPhysiological relevanceLamellipodial expansionVesiclesTetheringExocystMembraneFusionFurther showTetherFusion modeFateComplexes
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