2021
Effect of Mavacamten on Echocardiographic Features in Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy
Hegde SM, Lester SJ, Solomon SD, Michels M, Elliott PM, Nagueh SF, Choudhury L, Zemanek D, Zwas DR, Jacoby D, Wang A, Ho CY, Li W, Sehnert AJ, Olivotto I, Abraham TP. Effect of Mavacamten on Echocardiographic Features in Symptomatic Patients With Obstructive Hypertrophic Cardiomyopathy. Journal Of The American College Of Cardiology 2021, 78: 2518-2532. PMID: 34915982, DOI: 10.1016/j.jacc.2021.09.1381.Peer-Reviewed Original ResearchConceptsObstructive hypertrophic cardiomyopathySystolic anterior motionAnterior motionDiastolic functionHypertrophic cardiomyopathyN-terminal pro-B-type natriuretic peptideMitral valve systolic anterior motionPro-B-type natriuretic peptidePeak exercise oxygen consumptionLeft ventricular diastolic functionVentricular outflow tract obstructionKey echocardiographic parametersAtrial volume indexOutflow tract obstructionVentricular diastolic functionExercise oxygen consumptionEffect of mavacamtenMyocardial wall stressEXPLORER-HCMLVOT gradientEchocardiographic featuresEchocardiographic parametersLVOT obstructionTract obstructionExercise capacity
2014
The Imbrication Technique: An Alternative to the Sliding Leaflet Technique
Hashim PW, Assi R, Hashim SW. The Imbrication Technique: An Alternative to the Sliding Leaflet Technique. The Annals Of Thoracic Surgery 2014, 98: 1124-1126. PMID: 25193210, DOI: 10.1016/j.athoracsur.2014.01.066.Peer-Reviewed Original ResearchConceptsSystolic anterior motionLeaflet techniqueImbrication techniqueMitral valve repairAnterior motionConsecutive patientsTroublesome complicationValve repairLeaflet resectionHigh riskInconsistent efficacyReliable preventionResectionLeaflet tissuePreventionTechnical difficultiesComplicationsPatients
1996
Cardiac Risk of Noncardiac Surgery in Patients with Asymmetric Septal Hypertrophy
Haering M, Comunale M, Parker R, Lowenstein E, Douglas P, Krumholz H, Manning W. Cardiac Risk of Noncardiac Surgery in Patients with Asymmetric Septal Hypertrophy. Anesthesiology 1996, 85: 254-259. PMID: 8712439, DOI: 10.1097/00000542-199608000-00005.Peer-Reviewed Original ResearchConceptsAdverse cardiac eventsAsymmetric septal hypertrophyAdverse perioperative cardiac eventsPerioperative cardiac eventsCongestive heart failureCardiac eventsNoncardiac surgerySeptal hypertrophyHeart failureMajor surgeryCardiac riskMyocardial infarctionImportant independent risk factorOutflow tract gradientPercent of patientsDuration of surgeryIndependent risk factorLength of surgerySystolic anterior motionPrior myocardial infarctionCoronary artery diseaseType of anesthesiaAnterior mitral leafletEmergent cardioversionTract gradient
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