2024
Circumscribed Masses
Harigopal M, Raghu M, Pham R, Rende A, Podany P, Andrejeva L. Circumscribed Masses. 2024, 11-55. DOI: 10.1007/978-3-031-65711-5_2.Peer-Reviewed Original ResearchTerminal duct lobular unitsEncapsulated papillary carcinomaInvasive ductal carcinomaCircumscribed massFibroepithelial neoplasmsStromal componentsScreening mammographyPhyllodes tumorFibroepithelial lesionsPapillary carcinomaDuctal carcinomaInvasive carcinomaComplicated cystsCellular fibroadenomaHigh-grade invasive ductal carcinomaBI-RADSDuctal carcinoma in situOuter layer of myoepithelial cellsAggressive breast malignancyBasal-like carcinomasBenign fibroepithelial lesionsBenign fibroepithelial neoplasmBorderline phyllodes tumorMalignant phyllodes tumorSmooth muscle metaplasia
2021
3D Model of the Early Melanoma Microenvironment Captures Macrophage Transition into a Tumor-Promoting Phenotype
Pizzurro GA, Liu C, Bridges K, Alexander AF, Huang A, Baskaran JP, Ramseier J, Bosenberg MW, Mak M, Miller-Jensen K. 3D Model of the Early Melanoma Microenvironment Captures Macrophage Transition into a Tumor-Promoting Phenotype. Cancers 2021, 13: 4579. PMID: 34572807, PMCID: PMC8471848, DOI: 10.3390/cancers13184579.Peer-Reviewed Original ResearchTumor-associated macrophagesMelanoma tumor microenvironmentTumor microenvironmentTumor-promoting phenotypeAnti-tumor activityImmunosuppressive stateDisease progressionCo-culture systemImmune responseImmune activitySecretion profileDirect cell-cell interactionsMelanoma tumorsStromal componentsMacrophage transitionStromal cellsTumor cellsMelanoma cells
2020
Expression of lymphoid enhancer-binding factor 1 in breast fibroepithelial lesions
Chen PH, Bossuyt V, Reisenbichler E. Expression of lymphoid enhancer-binding factor 1 in breast fibroepithelial lesions. Human Pathology 2020, 108: 68-75. PMID: 33245988, DOI: 10.1016/j.humpath.2020.11.009.Peer-Reviewed Original ResearchConceptsMalignant phyllodes tumorPhyllodes tumorBenign tumorsLymphoid enhancer-binding factor 1Fibroepithelial lesionsTissue microarrayEnhancer-binding factor 1LEF-1 expressionMalignant tumorsBorderline/malignant phyllodes tumorsΒ-cateninStromal componentsNuclear expressionWorld Health Organization criteriaMetastatic phyllodes tumorWnt/β-catenin pathway activationAlternative treatment optionBorderline phyllodes tumorWnt/β-catenin pathwayFactor 1Β-catenin pathway activationE-cadherin immunohistochemistryWnt/β-catenin signalingΒ-catenin pathwayNuclear β-catenin staining
2017
The deleterious interplay between tumor epithelia and stroma in cholangiocarcinoma
Cadamuro M, Stecca T, Brivio S, Mariotti V, Fiorotto R, Spirli C, Strazzabosco M, Fabris L. The deleterious interplay between tumor epithelia and stroma in cholangiocarcinoma. Biochimica Et Biophysica Acta (BBA) - Molecular Basis Of Disease 2017, 1864: 1435-1443. PMID: 28757170, PMCID: PMC6386155, DOI: 10.1016/j.bbadis.2017.07.028.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTumor reactive stromaReactive stromaMain cellular componentsDeleterious interplayCyto/chemokinesCellular componentsParacrine signalsPrognosis of cholangiocarcinomaTumor epithelial cellsCell interactionsEarly invasivenessJesus BanalesMarco MarzioniNicholas LaRussoPeter JansenDifferent cell elementsEpithelial cellsEpithelial malignanciesTumor behaviorTumor epitheliumGrowth factorNeoplastic cellsTumor progressionCentral roleStromal components
2015
The Influence of Host Factors on the Prognosis of Breast Cancer: Stroma and Immune Cell Components as Cancer Biomarkers.
Karn T, Pusztai L, Rody A, Holtrich U, Becker S. The Influence of Host Factors on the Prognosis of Breast Cancer: Stroma and Immune Cell Components as Cancer Biomarkers. Current Cancer Drug Targets 2015, 15: 652-64. PMID: 26452382, DOI: 10.2174/156800961508151001101209.Peer-Reviewed Original ResearchConceptsBreast cancerPredictive markerImmune cellsStromal componentsHER2-positive breast cancerHigh lymphocytic infiltrationPositive breast cancerHER2-positive cancersImmune cell componentsNovel therapeutic optionsType breast cancerBreast cancer subtypesHost immunological responseImmunotherapeutic regimensClinical courseImmune markersLymphocytic infiltrationPositive cancersTherapeutic optionsInflammatory cellsClinical subtypingImmunological parametersClinical trialsImmune parametersImmunological response
2014
Development of the Fetal Bone Marrow Niche and Regulation of HSC Quiescence and Homing Ability by Emerging Osteolineage Cells
Coşkun S, Chao H, Vasavada H, Heydari K, Gonzales N, Zhou X, de Crombrugghe B, Hirschi KK. Development of the Fetal Bone Marrow Niche and Regulation of HSC Quiescence and Homing Ability by Emerging Osteolineage Cells. Cell Reports 2014, 9: 581-590. PMID: 25310984, PMCID: PMC4266564, DOI: 10.1016/j.celrep.2014.09.013.Peer-Reviewed Original ResearchConceptsOsteolineage cellsHematopoietic stem cellsHSC developmentCellular componentsAdult-repopulating hematopoietic stem cellsBone marrow nicheEmbryonic day 16.5HSC quiescenceMultilineage progenitorsSpecialized nichesNiche formationFetal bone marrow cellsHSC activityMarrow nicheMultilineage coloniesStem cellsBone marrow cellsDay 16.5NicheHSC proliferationHoming abilityMarrow cellsCellsBone marrowStromal components
2012
Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma
Stranford S, Ruddle NH. Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma. Frontiers In Immunology 2012, 3: 350. PMID: 23230435, PMCID: PMC3515885, DOI: 10.3389/fimmu.2012.00350.Peer-Reviewed Original ResearchSecondary lymphoid organsFollicular dendritic cellsHigh endothelial venulesLymph nodesDendritic cellsChronic inflammationLymphoid organsLymphoid tissueEndothelial venulesTertiary lymphoid organsAnti-tumor responseEctopic lymphoid tissueLymph node stromaTertiary lymphoid tissueNon-lymphoid organsLymphatic vesselsAutoimmune activityGraft rejectionAutoimmune responseInflammatory signalsTransgenic miceTherapeutic interventionsReticular cellsStromal componentsVivo real time
2010
Glandular Lesions of the Cervix
Chhieng D, Hui P. Glandular Lesions of the Cervix. Current Clinical Pathology 2010, 59-80. DOI: 10.1007/978-1-60761-164-6_4.Peer-Reviewed Original Research
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