2022
Exploring the clinical and genetic associations of adult weight trajectories using electronic health records in a racially diverse biobank: a phenome-wide and polygenic risk study
Xu J, Johnson JS, Signer R, Consortium E, Birgegård A, Jordan J, Kennedy MA, Landén M, Maguire SL, Martin NG, Mortensen PB, Petersen LV, Thornton LM, Bulik CM, Huckins LM. Exploring the clinical and genetic associations of adult weight trajectories using electronic health records in a racially diverse biobank: a phenome-wide and polygenic risk study. The Lancet Digital Health 2022, 4: e604-e614. PMID: 35780037, PMCID: PMC9612590, DOI: 10.1016/s2589-7500(22)00099-1.Peer-Reviewed Original ResearchConceptsElectronic health recordsPolygenic risk scoresWeight trajectoriesDepression polygenic risk scoresObesity polygenic risk scoresHealth recordsWeight changeUK BiobankIndividual health statusLower disease riskGenetic associationPatient populationUS National InstitutesWeight managementStable weightRisk scoreHealthy populationHealth statusAnorexia nervosaBioMe BiobankDisease riskDisorder diagnosisMental healthWeight lossPhenome-wide association study
2021
Does your past define you? How weight histories are associated with child eating-disorder psychopathology
Lydecker JA, Rossa ET, Grilo CM. Does your past define you? How weight histories are associated with child eating-disorder psychopathology. Eating And Weight Disorders - Studies On Anorexia, Bulimia And Obesity 2021, 27: 515-524. PMID: 33851327, PMCID: PMC8511348, DOI: 10.1007/s40519-021-01167-8.Peer-Reviewed Original Research
2020
A Low ω-6 to ω-3 PUFA Ratio (n–6:n–3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth
Van Name MA, Savoye M, Chick JM, Galuppo BT, Feldstein AE, Pierpont B, Johnson C, Shabanova V, Ekong U, Valentino PL, Kim G, Caprio S, Santoro N. A Low ω-6 to ω-3 PUFA Ratio (n–6:n–3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth. Journal Of Nutrition 2020, 150: 2314-2321. PMID: 32652034, PMCID: PMC7467848, DOI: 10.1093/jn/nxaa183.Peer-Reviewed Original ResearchConceptsFatty liver diseasePNPLA3 rs738409 genotypeLiver diseaseAlanine aminotransferaseRs738409 genotypeInsulin sensitivityObese youthNonalcoholic fatty liver diseaseGenotype groupsWhole-body insulin sensitivityBody insulin sensitivityLinoleic acid metabolitesHepatic fat fractionMann-Whitney U testDiet imbalanceNormocaloric dietPrimary outcomeLDL cholesterolDietary interventionFatty liverUnblinded studyObese adolescentsPUFA dietMetabolic parametersStable weight
2003
Weight maintenance and relapse in obesity: a qualitative study
Byrne S, Cooper Z, Fairburn C. Weight maintenance and relapse in obesity: a qualitative study. International Journal Of Obesity 2003, 27: 955-962. PMID: 12861237, DOI: 10.1038/sj.ijo.0802305.Peer-Reviewed Original ResearchConceptsObese womenSuccessful weight maintainersSuccessful weight lossHealthy weight womenPsychological factorsDichotomous thinking styleWeight regainersWeight regainWeight maintainersWeight maintenanceStable weightWeight goalsWeight controlHealthy rangeProspective designWeight lossWomenCertain psychological factorsLack of vigilanceObesityRegainersLow weightThinking stylesStudy needQualitative study
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply