2023
Diagnosis of Chronic Kidney Disease and Assessing Glomerular Filtration Rate
Aklilu A. Diagnosis of Chronic Kidney Disease and Assessing Glomerular Filtration Rate. 2023, 107: 641-658. PMID: 37258004, DOI: 10.1016/j.mcna.2023.03.001.Peer-Reviewed Original Research
2019
Sarcopenia Strongly Affects Serum Levels of Cystatin C in Patients with Heart Failure
Ivey-Miranda J, Stewart B, Gomez N, Barnett J, Thomas A, Wycallis E, Pattoli M, Struyk G, Fleming J, Shamlian P, Raghavendra P, Mahoney D, Griffin M, Rao V, Testani J. Sarcopenia Strongly Affects Serum Levels of Cystatin C in Patients with Heart Failure. Journal Of Cardiac Failure 2019, 25: s20-s21. DOI: 10.1016/j.cardfail.2019.07.059.Peer-Reviewed Original ResearchGlomerular filtration rateSerum cystatin CSerum cystatin C levelsHeart failureCystatin C levelsCystatin CSerum creatinineMuscle massCreatinine clearanceSerum levelsCystatin C serum levelsDecompensated heart failureC levelsC serum levelsUrine creatinine excretionLow muscle massCreatinine excretion rateRenal functionLess muscle massLowest tertileUse of creatinineCreatinine excretionFiltration rateUnivariate analysisUrine collection
2013
Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction: The ROSE Acute Heart Failure Randomized Trial
Chen HH, Anstrom KJ, Givertz MM, Stevenson LW, Semigran MJ, Goldsmith SR, Bart B, Bull DA, Stehlik J, LeWinter MM, Konstam MA, Huggins GS, Rouleau JL, O'Meara E, Tang WH, Starling RC, Butler J, Deswal A, Felker GM, O'Connor CM, Bonita RE, Margulies KB, Cappola TP, Ofili EO, Mann DL, Dávila-Román VG, McNulty SE, Borlaug BA, Velazquez EJ, Lee KL, Shah MR, Hernandez AF, Braunwald E, Redfield MM. Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction: The ROSE Acute Heart Failure Randomized Trial. JAMA 2013, 310: 2533-2543. PMID: 24247300, PMCID: PMC3934929, DOI: 10.1001/jama.2013.282190.Peer-Reviewed Original ResearchConceptsLow-dose dopamineAcute heart failureCumulative urine volumeRenal dysfunctionCystatin C levelsHeart failureRenal functionUrine volumeDiuretic therapyPlacebo-controlled clinical trialEnd pointPooled placebo groupCoprimary end pointsSecondary end pointsHours of admissionC levelsSerum cystatin CDose dopaminePlacebo groupActive treatmentClinical outcomesRandomized trialsClinical trialsCystatin CMAIN OUTCOME
2012
Spot Urine Albumin to Creatinine Ratio and Serum Cystatin C are Effective for Detection of Diabetic Nephropathy in Childhood Diabetic Patients
Chae H, Shin J, Kwon A, Kim H, Kim D. Spot Urine Albumin to Creatinine Ratio and Serum Cystatin C are Effective for Detection of Diabetic Nephropathy in Childhood Diabetic Patients. Journal Of Korean Medical Science 2012, 27: 784-787. PMID: 22787375, PMCID: PMC3390728, DOI: 10.3346/jkms.2012.27.7.784.Peer-Reviewed Original ResearchConceptsAlbumin-to-creatinine ratioUrine albumin-to-creatinine ratioSpot urine albumin to creatinine ratioSerum CysCUrine microalbuminDiabetic nephropathyCreatinine clearanceCreatinine ratioCystatin CDiabetic patientsDetection of diabetic nephropathyUrinary albumin-to-creatinine ratioPresence of diabetic nephropathyAssessment of diabetic nephropathySerum cystatin CUrine albumin excretionSpot urinary albumin-to-creatinine ratioAssessment of microalbuminuriaROC curve analysisAlbumin excretionSerum creatinineRenal functionUrine collectionDiagnostic accuracyClinical value
2007
The Clinical Usefulness of Cystatin C in Evaluating Renal Function in Children with Various Renal Diseases
Kim K, Kim J, Shin J, Hwang Y, Cheung I, Lee J, Lim J. The Clinical Usefulness of Cystatin C in Evaluating Renal Function in Children with Various Renal Diseases. Childhood Kidney Diseases 2007, 11: 161-167. DOI: 10.3339/jkspn.2007.11.2.161.Peer-Reviewed Original ResearchSerum cystatin CCystatin CCreatinine clearanceSerum creatinineRenal diseaseRenal impairmentClinical useEarly detection of renal impairmentCorrelated to creatinine clearanceEndogenous markerDetection of renal impairmentUsefulness of cystatin CProgression of renal diseaseMeasuring serum creatinineEvaluate renal functionRenal functionPediatric patientsDecreased GFRFiltration rateDiagnostic accuracyGroup 2CreatinineCystatin C.GFRSerum
2004
Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement
Knight EL, Verhave JC, Spiegelman D, Hillege HL, De Zeeuw D, Curhan GC, De Jong PE. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney International 2004, 65: 1416-1421. PMID: 15086483, DOI: 10.1111/j.1523-1755.2004.00517.x.Peer-Reviewed Original ResearchConceptsSerum cystatin C levelsCystatin C levelsSerum creatinine levelsSerum cystatin CRenal functionCreatinine levelsCreatinine clearanceCystatin CSerum creatininePartial Spearman correlationsC levelsCigarette smokingHigh serum C-reactive protein levelsHigher serum cystatin C levelsSerum C-reactive protein levelsC-reactive protein levelsSerum CRP levelsCurrent cigarette smokingRenal function measurementsSpearman correlationCross-sectional studyYears of ageCRP levelsMultivariate linear regression modelMale gender
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